A combination of cefuroxime and N-acetyl-cysteine for the treatment of lower respiratory tract infections in children

Abstract

One hundred and three children with lower respiratory tract infections were treated with a combination of cefuroxime and N-acetyl-cysteine. Positive clinical results were obtained in 100 patients, symptoms being completely relieved in 58 and distinct improvement produced in 42. Chest x-rays provided objective evidence of recovery or improvement in these 100 patients. Of the 72 pathogenic strains isolated before treatment in the trial population as a whole, none were still detectable at the end of treatment. No side effects or adverse reactions of any kind were observed.