Management of twin pregnancies: Remaining challenges and unanswered questions
- PMID: 40084925
- PMCID: PMC12255925
- DOI: 10.1002/ijgo.70070
Management of twin pregnancies: Remaining challenges and unanswered questions
Abstract
Several professional societies have published guidelines on twin pregnancies over the past few years. These documents provide recommendations on antenatal surveillance and management of twin pregnancies. At the same time, these guidelines identify several key areas where evidence is limited and additional research is needed. In the present review, we summarize available evidence regarding some of these key areas, including the screening and prevention of preterm birth, the definition and management of fetal growth restriction, the diagnosis and management of gestational diabetes, the optimal maternal gestational weight gain, and the mode and timing of delivery. In addition, we describe several online tools related to these areas that can empower individuals with twin pregnancies and assist care providers in counseling these patients.
Keywords: conflicting; controversies; debate; multifetal; questions; twin.
© 2025 The Author(s). International Journal of Gynecology & Obstetrics published by John Wiley & Sons Ltd on behalf of International Federation of Gynecology and Obstetrics.
Conflict of interest statement
The authors have no conflicts of interest or potential conflicts of interest relevant to this article to disclose.
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References
-
- Chauhan SP, Scardo JA, Hayes E, Abuhamad AZ, Berghella V. Twins: prevalence, problems, and preterm births. Am J Obstet Gynecol. 2010;203(4):305‐315. - PubMed
-
- Osterman MJK, Hamilton BE, Martin JA, Driscoll AK, Valenzuela CP. Births: final data for 2022. Natl Vital Stat Rep. 2024;73(2):1‐56. - PubMed
-
- Statistics Canada . Table 13‐10‐0428‐01 Live births and fetal deaths (stillbirths), by type of birth (single or multiple). 2024. doi: 10.25318/1310042801-eng - DOI
-
- Salem SY, Kibel M, Asztalos E, Zaltz A, Barrett J, Melamed N. Neonatal outcomes of low‐risk, late‐preterm twins compared with late‐preterm singletons. Obstet Gynecol. 2017;130(3):582‐590. - PubMed
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