Kidney and Lungs: Do they Cross-talk?

Abstract

The kidneys and lungs, often studied in isolation, are integral organs in maintaining homeostasis within the human body. However, the lung and kidney have multiple shared physiological and pathological pathways. It is important to understand these complex interactions and the cross-talk to manage patients, especially in critical care. This review delves into the intricate relationship between the kidneys and lungs, shedding light on how dysfunction in one organ can profoundly impact the other. It explores shared mechanisms, molecular mediators, and clinical implications, demonstrating the significance of understanding this cross-talk. By elucidating the nuanced interplay between the kidneys and lungs, we hope to pave the way for more holistic approaches to the diagnosis and treatment of diseases, ultimately enhancing patient care.