Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2025 Apr;4(4):101658.
doi: 10.1016/j.jacadv.2025.101658. Epub 2025 Mar 14.

Aerobic Exercise and HFrEF: Impact of Sex and Biological Age

Affiliations
Editorial

Aerobic Exercise and HFrEF: Impact of Sex and Biological Age

Branden L Nguyen et al. JACC Adv. 2025 Apr.
No abstract available

Keywords: aging; exercise training; heart failure; sex as a biological variable.

PubMed Disclaimer

Conflict of interest statement

Funding support and author disclosures Dr Nguyen is currently funded by NIH T32 AG000279. Dr Clayton is currently funded by NIH R00 HL159241. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract

Comment on

  • doi: 10.1016/j.jacadv.2025.101659

References

    1. GDP Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392:1789–1858. doi: 10.1016/S0140-6736(18)32279-7. - DOI - PMC - PubMed
    1. Shahim B., Kapelios C.J., Savarese G., Lund L.H. Global public health burden of heart failure: an updated review. Card Fail Rev. 2023;9:e11. doi: 10.15420/cfr.2023.05. - DOI - PMC - PubMed
    1. Bozkurt B., Coats A.J.S., Tsutsui H., et al. Universal definition and classification of heart failure: a report of the heart failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the universal definition of heart failure. J Card Fail. 2021;23:352–380. doi: 10.1016/j.cardfail.2021.01.022. - DOI
    1. Murphy S.P., Ibrahim N.E., Januzzi J.L. Heart failure with reduced ejection fraction: a review. JAMA. 2020;324:488–504. doi: 10.1001/jama.2020.10262. - DOI - PubMed
    1. Joseph P., Dokainish H., McCready T., et al. A multinational registry to study the characteristics and outcomes of heart failure patients: the global congestive heart failure (G-CHF) registry. Am Heart J. 2020;227:56–63. doi: 10.1016/j.ahj.2020.06.002. - DOI - PubMed

Publication types

LinkOut - more resources