Survey on the impact of WHO 2021 classification of brain tumors on adult glioma management in Africo-Asian region

Abstract

The 2021 WHO classification of central nervous system (CNS) tumors introduced significant changes based on molecular and biological tumor characteristics, aiming to improve prognostication and enable more precise treatment approaches. This study investigated the awareness, adoption, and impact of the new classification on adult glioma management among healthcare professionals in Africo-Asian region. Through a structured survey questionnaire distributed across these regions, assessment of the level of awareness, diagnostic changes, challenges faced, and future perspectives among respondents was done. The survey received responses from 56 participants. Findings revealed that while 67.85% of respondents from Asia and 32.15% from Africa reported awareness of the new classification, both groups faced significant challenges in accessing molecular diagnostics, with financial constraints limiting widespread implementation. This paper provides insights into the current state of brain glioma management in resource-limited settings and discusses the potential need for further refinements in the WHO classification of CNS tumors and adult glioma management guidelines to address these disparities.