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Comment
. 2025 Apr;12(4):e236-e238.
doi: 10.1016/S2352-3026(25)00040-7. Epub 2025 Mar 13.

CAR T-cell therapy in LMICs: approval of talicabtagene autoleucel in India

Luca Paruzzo  1 , Marco Ruella  2
Affiliations
Comment

CAR T-cell therapy in LMICs: approval of talicabtagene autoleucel in India

Luca Paruzzo et al. Lancet Haematol. 2025 Apr.
No abstract available

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Conflict of interest statement

MR reports grants and personal fees from viTToria Bio; non-financial support from Beckman Coulter and ORFLO; personal fees from GSK, Bristol Myers Squibb, Sana, NanoString, GLG, and Guidepoint; grants from AbClon and ONI; and multiple patents on CAR T immunotherapy managed by the University of Pennsylvania that are pending, issued, licensed, and with royalties paid from viTToria Bio, Novartis, and Tmunity. LP declares no competing interests.

Comment on

  • Talicabtagene autoleucel for relapsed or refractory B-cell malignancies: results from an open-label, multicentre, phase 1/2 study.
    Jain H, Karulkar A, Kalra D, Ravikumar S, Shah S, Firfiray A, Pendhari J, Jaiswal AK, Khan A, Sundharam M, Vaibhaw A, Saroha A, Rajyopadhye S, Basu M, Asija S, Chowdhury A, Beher R, Banik A, Dwivedi A, Purwar S, Narula G, Banavali S, Jain N, Highfill SL, Stroncek D, Fry T, Melinkeri S, Wilson L, Agarwal N, Aribandi A, Boyella PK, Shah NN, Neelapu SS, Sengar M, Purwar R; CAR-T clinical trial group. Jain H, et al. Lancet Haematol. 2025 Apr;12(4):e282-e293. doi: 10.1016/S2352-3026(24)00377-6. Epub 2025 Mar 13. Lancet Haematol. 2025. PMID: 40090352 Clinical Trial.

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