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Review
. 2025 Jul 1;99(1):1-9.
doi: 10.1097/TA.0000000000004561. Epub 2025 Mar 17.

Management of perforated peptic ulcer: What you need to know

Samir Rasslan  1 , Raul Coimbra, Roberto Rasslan, Edivaldo M Utiyama
Affiliations
Review

Management of perforated peptic ulcer: What you need to know

Samir Rasslan et al. J Trauma Acute Care Surg. .

Abstract

Despite therapeutic advancements and the significant efficacy of medical management, peptic ulcer disease still affects millions of people. Elective surgical treatment, once a common intervention in General Surgery departments, is now nearly obsolete. Surgical treatment is reserved solely for complications, which occur in approximately 10% to 20% of cases. Perforation is the most common indication for surgery in peptic ulcer disease and accounts for nearly 40% of deaths from the disease. Treatment success depends on various factors, with early diagnosis and immediate surgical intervention being highlighted. Perforation is associated with a high incidence of morbidity and mortality. This article aims to analyze the different aspects related to the treatment of perforated peptic ulcers and define the best therapeutic approaches.

Keywords: emergency surgery; gastric resection; gastroduodenal ulcer; omental patch repair; perforated peptic ulcer.

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References

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