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. 2025 Mar 14;13(3):e70320.
doi: 10.1002/ccr3.70320. eCollection 2025 Mar.

Cervical Vagal Schwannoma: A Case Report and Literature Review

Sunil Thatal  1 , Susmin Karki  2 , Asmita Parajuli  2 , Yamuna Agrawal  3 , Deepak Paudel  4
Affiliations

Cervical Vagal Schwannoma: A Case Report and Literature Review

Sunil Thatal et al. Clin Case Rep. .

Abstract

Vagal schwannoma is a benign tumor that can occasionally develop into malignant degeneration from the Schwann cells surrounding the cranial, peripheral, and autonomic nerves. The schwannomas arising in the head and neck region are rare, and rarer is their origin from the cervical vagus nerve. Despite being challenging, multiple treatment options are available, including observation, complete tumor excision with nerve transaction, and nerve preservation, depending on clinicoradiological factors. The cervical vagal schwannoma is a rare entity. We report a rare case of a 50-year-old female with painless swelling on the right side of the neck associated with mild discomfort during swallowing, diagnosed as cervical vagal schwannoma.

Keywords: benign tumor; cervical schwannoma; schwannoma; vagal schwannoma.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
CT angiography and CT of the head and neck showed heterogeneously enhancing soft tissue mass in the right parapharyngeal space.
FIGURE 2
FIGURE 2
(A) Intraoperative view of the right vagal schwannoma. (B) Intraoperative view after resection of the vagal schwannoma. (C) A gross specimen of resected vagal schwannoma shows a single, globular, capsulated, gray‐white to gray, brown, irregular soft tissue of size measuring 11 × 6 × 5 cm.
FIGURE 3
FIGURE 3
The figures show histologic features of benign peripheral nerve sheath tumors consistent with ancient Schwannoma. A, Antoni A; B, Antoni B.
See this image and copyright information in PMC

References

    1. Biswas D., Marnane C. N., Mal R., and Baldwin D., “Extracranial Head and Neck Schwannomas—A 10‐Year Review,” Auris Nasus Larynx 34, no. 3 (2007): 353–359, 10.1016/j.anl.2007.01.006. - DOI - PubMed
    1. Green J. D., Olsen K. D., DeSanto L. W., and Scheithauer B. W., “Neoplasms of the Vagus Nerve,” Laryngoscope 98, no. 6 Pt 1 (1988): 648–654, 10.1288/00005537-198806000-00014. - DOI - PubMed
    1. Yumoto E., Nakamura K., Mori T., and Yanagihara N., “Parapharyngeal Vagal Neurilemmoma Extending to the Jugular Foramen,” Journal of Laryngology and Otology 110, no. 5 (1996): 485–489, 10.1017/s0022215100134061. - DOI - PubMed
    1. Lahoti B. K., Kaushal M., Garge S., and Aggarwal G., “Extra Vestibular Schwannoma: A Two Year Experience,” Indian Journal of Otolaryngology and Head & Neck Surgery 63, no. 4 (2011): 305–309, 10.1007/s12070-011-0154-5. - DOI - PMC - PubMed
    1. Langner E., Del Negro A., Akashi H. K., Araújo P. P. C., Tincani A. J., and Martins A. S., “Schwannomas in the Head and Neck: Retrospective Analysis of 21 Patients and Review of the Literature,” Sao Paulo Medical Journal = Revista Paulista de Medicina 125, no. 4 (2007): 220–222, 10.1590/s1516-31802007000400005. - DOI - PMC - PubMed

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