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Case Reports
. 2025 Feb 10;10(4):101736.
doi: 10.1016/j.adro.2025.101736. eCollection 2025 Apr.

First Application of Boron Neutron Capture Therapy for Recurrent Clival Chordoma With Brainstem Abutment

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Case Reports

First Application of Boron Neutron Capture Therapy for Recurrent Clival Chordoma With Brainstem Abutment

Hung-Ruei Liao et al. Adv Radiat Oncol. .
No abstract available

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Figure 1
Figure 1
(A) Axial and (B) coronal views of the brain positron emission tomography scan on August 17, 2023, showing a 1.7 × 1.4 cm nodule with a tumor-to-normal tissue ratio of 3.69. (C) Transverse and (D) coronal views of the brain positron emission tomography scan on January 19, 2024, showing a regressive change of the tumor with a tumor-to-normal tissue ratio of 2.83.
Figure 2
Figure 2
T2-weighted brain magnetic resonance imaging axial view with a 4 mm slice thickness for clival chordoma. (A) Imaging on June 24, 2023, before boron neutron capture therapy (BNCT), (B) on December 22, 2023, after the first BNCT, and (C) on May 13, 2024, after the second BNCT. In all 3 series (A-C), image 2 represents the slice showing the tumor at its largest dimension, while images 1 and 3 correspond to magnetic resonance imaging slices taken 4 mm above and below image 2, respectively.

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References

    1. McMaster M.L., Goldstein A.M., Bromley C.M., Ishibe N., Parry DM. Chordoma: Incidence and survival patterns in the United States, 1973-1995. Cancer Causes Control. 2001;12:1–11. - PubMed
    1. Ulici V., Hart J. Chordoma: A review and differential diagnosis. Arch Path Lab. 2021;146:386–395. - PubMed
    1. Iannalfi A., Riva G., Ciccone L., Orlandi E. The role of particle radiotherapy in the treatment of skull base tumors. Front Oncol. 2023;13 - PMC - PubMed
    1. Zhou J., Yang B., Wang X., Jing Z. Comparison of the effectiveness of radiotherapy with photons and particles for chordoma after surgery: A meta-analysis. World Neurosurg. 2018;117:46–53. - PubMed
    1. Saito T., Mizumoto M., Oshiro Y., et al. Systematic review and meta-analysis of particle beam therapy versus photon radiotherapy for skull base chordoma: TRP-Chordoma 2024. Cancers (Basel) 2024;16:2569. - PMC - PubMed

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