Lung Function Decline in Smokers with Normal Spirometry: The Devastating Impact of Lung Attacks

Yunus Çolak^{1

2

3}

Affiliations

¹ Department of Respiratory Medicine.
² Copenhagen General Population Study Copenhagen University Hospital - Herlev and Gentofte Copenhagen, Denmark.
³ Faculty of Health and Medical Sciences University of Copenhagen Copenhagen, Denmark.

Editorial

Yunus Çolak. Am J Respir Crit Care Med. 2025 Jun.

. 2025 Jun;211(6):891-892.

doi: 10.1164/rccm.202501-0223ED.

Yunus Çolak^{1

2

3}

¹ Department of Respiratory Medicine.
² Copenhagen General Population Study Copenhagen University Hospital - Herlev and Gentofte Copenhagen, Denmark.
³ Faculty of Health and Medical Sciences University of Copenhagen Copenhagen, Denmark.

No abstract available

Comment on

Respiratory Exacerbations and Lung Function Decline in People with Smoking History and Normal Spirometry.
Fortis S, Strand M, Bhatt SP, Ten Eyck P, Wendt L, Parekh T, Han MK, Hokanson JE, Kinney G, Curtis JL, Bowler RP, Wan ES, Kunisaki KM, Wendt CH, Regan E, Dransfield M, Crapo JD, Silverman EK, Comellas AP; COPDGene Investigators. Fortis S, et al. Am J Respir Crit Care Med. 2025 Jun;211(6):957-965. doi: 10.1164/rccm.202401-0023OC. Am J Respir Crit Care Med. 2025. PMID: 39946437

1. Celli BR, Wedzicha JA. Update on clinical aspects of chronic obstructive pulmonary disease. N Engl J Med . 2019;381:1257–1266. - PubMed
1. Wedzicha JA, Seemungal TA. COPD exacerbations: defining their cause and prevention. Lancet . 2007;370:786–796. - PMC - PubMed
1. Aaron SD, Donaldson GC, Whitmore GA, Hurst JR, Ramsay T, Wedzicha JA. Time course and pattern of COPD exacerbation onset. Thorax . 2012;67:238–243. - PubMed
1. Agustí A, Celli BR, Criner GJ, Halpin D, Anzueto A, Barnes P, et al. Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Am J Respir Crit Care Med . 2023;207:819–837. - PMC - PubMed
1. Agusti A, Hogg JC. Update on the pathogenesis of chronic obstructive pulmonary disease. N Engl J Med . 2019;381:1248–1256. - PubMed