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Review
. 2025 Aug;86(2):119-126.
doi: 10.1016/j.jjcc.2025.03.009. Epub 2025 Mar 17.

Tricuspid regurgitation: Innovation, current landscape, and future perspective of transcatheter tricuspid valve interventions

Atsushi Sugiura  1 , Tetsu Tanaka  2 , Refik Kavsur  2 , Can Öztürk  2 , Johanna Vogelhuber  2 , Miriam Silaschi  3 , Marcel Weber  2 , Sebastian Zimmer  2 , Georg Nickenig  2
Affiliations
Free article
Review

Tricuspid regurgitation: Innovation, current landscape, and future perspective of transcatheter tricuspid valve interventions

Atsushi Sugiura et al. J Cardiol. 2025 Aug.
Free article

Abstract

Tricuspid regurgitation (TR) is a prevalent cardiovascular disease necessitating innovative treatments. Assessing comorbidities, such as right ventricular dysfunction, is pivotal for the therapeutic strategy. Preprocedural echocardiographic assessments are crucial for achieving optimal TR reduction. Transcatheter interventions have emerged as less invasive therapies. Tricuspid transcatheter edge-to-edge repair is the predominant technology, proven safe and effective in reducing TR. Additionally, transcatheter tricuspid valve replacement and direct annuloplasty technologies have been developed and recognized as attractive alternatives, each with unique advantages. This review discusses the innovation, current landscape, and future perspective of transcatheter tricuspid valve interventions for treating TR.

Keywords: Transcatheter annuloplasty; Transcatheter edge-to-edge repair; Transcatheter tricuspid valve intervention; Transcatheter tricuspid valve replacement; Tricuspid regurgitation.

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Conflict of interest statement

Declaration of competing interest Atsushi Sugiura has received research funding from Edwards Lifesciences and lecture or proctoring honoraria from Abbott and Edwards Lifesciences. Tetsu Tanaka has received grants from the Japanese College of Cardiology and the Uehara Memorial Foundation and honoraria from Canon Medical Systems. Marcel Weber has received lecture or proctoring fees from Abbott and Edwards Lifesciences. Georg Nickenig has received research funding from the Deutsche Forschungsgemeinschaft, the German Federal Ministry of Education and Research, Abbott, Edwards Lifesciences, Medtronic, and St. Jude Medical and has received honoraria for lectures or advisory boards from Abbott, Edwards Lifesciences, Medtronic, and St. Jude Medical. The other authors have no conflicts of interest.

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