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. 1985 May;90(2):107-11.
doi: 10.1007/BF00436860.

Studies of the effects of spherulin from Coccidioides immitis on human polymorphonuclear leukocytes

J N Galgiani

Studies of the effects of spherulin from Coccidioides immitis on human polymorphonuclear leukocytes

J N Galgiani. Mycopathologia. 1985 May.

Abstract

The effects of spherule lysate (spherulin) on human polymorphonuclear leukocyte (PMN) function was examined. PMN adherence to glass and capping was increased by spherulin, findings which may account for spherulin's interference with complement-mediated migration through cellulose ester filters. In contrast, PMN attachment to yeast, killing of bacteria, and effects on spherules were virtually unaffected by spherulin, suggesting that it does not directly inhibit PMN antimicrobial function.

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References

    1. Am Rev Respir Dis. 1978 Apr;117(4):727-71 - PubMed
    1. Blood. 1975 Dec;46(6):901-11 - PubMed
    1. Proc Natl Acad Sci U S A. 1980 Jun;77(6):3499-503 - PubMed
    1. J Immunol Methods. 1978;24(3-4):389-93 - PubMed
    1. Sabouraudia. 1973 Nov;11(3):222-34 - PubMed

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