Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1985 May;10(5):703-11.
doi: 10.1007/BF00964408.

Glutathione peroxidase activity in surgical and autopsied human brains

Comparative Study

Glutathione peroxidase activity in surgical and autopsied human brains

K A Ansari et al. Neurochem Res. 1985 May.

Abstract

Glutathione peroxidase (GSHPx) activity was assayed in normal cerebral gray and white matter samples obtained from frontal, temporal, occipital and parietal lobes during surgical approach to an underlying lesion, and also in normal autopsied human frontal gray and white matter. GSHPx was assayed by a 2 step enzyme reaction which was monitored by following the oxidation of NADPH at 340 nm. It was found that all the brain samples studied contained GSHPx activity. Parietal lobe appeared to have the lowest GSHPx activity compared to temporal, occipital or frontal lobes. Mean enzyme activity in autopsied samples was comparable to that in surgical material. However, considerable loss of activity was observed after 10 years of tissue storage at -80 degrees C.

PubMed Disclaimer

References

    1. Anal Biochem. 1978 Jun 15;87(1):206-10 - PubMed
    1. Neurobiol Aging. 1982 Fall;3(3):173-8 - PubMed
    1. J Lipid Res. 1965 Oct;6(4):545-51 - PubMed
    1. J Biol Chem. 1957 Nov;229(1):189-97 - PubMed
    1. Arch Neurol. 1975 Feb;32(2):114-8 - PubMed

Publication types

MeSH terms