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Published Erratum
. 2025 Mar 25;122(12):e2504152122.
doi: 10.1073/pnas.2504152122. Epub 2025 Mar 20.

Correction for Xu et al., BCL6 promotes glioma and serves as a therapeutic target

No authors listed
Published Erratum

Correction for Xu et al., BCL6 promotes glioma and serves as a therapeutic target

No authors listed. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Fig. 4.
Fig. 4.
Identification of AXL as a target of BCL6. (A) Phospho-RTK array result showing the down-regulation of phosphorylated AXL in U87 cells with depletion of BCL6. Red boxes indicate the chemiluminescent signals in duplicate for p-EGFR (1), p-MET (2), p-AXL (3), and p-ROR2 (4). (B and C) qPCR (B) and western blot (C) results showing the down-regulation of AXL after BCL6 depletion in GBM cell lines. RNA and protein samples were harvested 36 and 72 h posttransfection, respectively. Data represent means ± SD (n = 3). (D) Immunofluorescence staining showing the correlated expression between Bcl6 and Axl in EGFP+ tumor cells (indicated by arrows) at the margin of tumors in KrasG12V (Upper) and KrasG12V/shBcl6 (Lower). (E) The ChIP-seq signals of RNA Pol2, MED1, H3K27ac, MAX, and MYC in U87 AXL locus were visualized using Integrative Genomics Viewer. The Y axis represents the value of reads per million. Gray and red bars indicate the template regions amplified by respective ChIP-qPCR primers. (F) ChIP-qPCR results showing the enrichment of BCL6 binding in AXL locus. Cells were fixed 2 h after the addition of fresh medium. The 5′ UTR region of BCL6 was applied as a positive control (PC). (G) Effect of either GFP-BCL6 or GFP-BCL6-ZF on AXL expression. (H) Effect of BCL6, NCoR, and BCoR silencing on AXL expression. (I) ChIP-qPCR results showing the enrichment of NCoR binding in AXL locus.
See this image and copyright information in PMC

Erratum for

  • BCL6 promotes glioma and serves as a therapeutic target.
    Xu L, Chen Y, Dutra-Clarke M, Mayakonda A, Hazawa M, Savinoff SE, Doan N, Said JW, Yong WH, Watkins A, Yang H, Ding LW, Jiang YY, Tyner JW, Ching J, Kovalik JP, Madan V, Chan SL, Müschen M, Breunig JJ, Lin DC, Koeffler HP. Xu L, et al. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3981-3986. doi: 10.1073/pnas.1609758114. Epub 2017 Mar 29. Proc Natl Acad Sci U S A. 2017. PMID: 28356518 Free PMC article.

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