Effectiveness of Upadacitinib in the Treatment of Chronic Hand Eczema and Nail-Associated Changes in a Patient With Atopic Dermatitis

Affiliations

¹ Dermatology Unit, Azienda Unità Sanitaria Locale-IRCCS of Reggio Emilia, Reggio Emilia, Italy.
² Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
³ Skin Cancer Center, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
⁴ Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Dermatology Clinic, Sapienza University of Rome, Rome, Italy.
⁵ IDI-IRCCS Istituto Dermopatico dell'Immacolata, Rome, Italy.

Laura Bonzano et al. Int J Dermatol. 2025 Sep.

. 2025 Sep;64(9):1692-1694.

doi: 10.1111/ijd.17673. Epub 2025 Mar 21.

¹ Dermatology Unit, Azienda Unità Sanitaria Locale-IRCCS of Reggio Emilia, Reggio Emilia, Italy.
² Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
³ Skin Cancer Center, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia, Italy.
⁴ Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Dermatology Clinic, Sapienza University of Rome, Rome, Italy.
⁵ IDI-IRCCS Istituto Dermopatico dell'Immacolata, Rome, Italy.

No abstract available

Keywords: atopic dermatitis; inflammatory diseases; nail disorders; tyrosine kinase inhibitor; upadacitinib.

References

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1. E. Held, R. Skoet, J. D. Johansen, and T. Agner, “The Hand Eczema Severity Index (HECSI): A Scoring System for Clinical Assessment of Hand Eczema. A Study of Inter‐ and Intraobserver Reliability,” British Journal of Dermatology 152, no. 2 (2005): 302–307.
1. W. Q. Chng and Y. W. Yew, “Nail Manifestations in Atopic Dermatitis: A Systematic Review,” International Journal of Dermatology 59, no. 6 (2020): 670–676.
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