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Comparative Study
. 1985 May;22(5):893-5.
doi: 10.1016/0091-3057(85)90543-x.

Cholecystokinin and bombesin suppress operant responding for food reward

Comparative Study

Cholecystokinin and bombesin suppress operant responding for food reward

A M Babcock et al. Pharmacol Biochem Behav. 1985 May.

Abstract

The effects of intraperitoneal injections of cholecystokinin (CCK) and bombesin (BBS) on food-rewarded operant responding were investigated. Response rates were significantly suppressed following administrations of CCK (0.7, 1.4, and 2.9 micrograms/kg). The effects appeared to be dose dependent. Responding was also suppressed following injections of BBS (6 and 16 micrograms/kg). These results confirm and extend previous findings concerning the possible function of these peptides.

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