Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Mar 21;20(3):e0319181.
doi: 10.1371/journal.pone.0319181. eCollection 2025.

A mixed-methods study protocol: Perinatal depression screening systems and outcomes in obstetrics clinics

Affiliations

A mixed-methods study protocol: Perinatal depression screening systems and outcomes in obstetrics clinics

Rachel Vanderkruik et al. PLoS One. .

Abstract

Perinatal depression (PND) is an underrecognized and underdiagnosed public health issue with long-term adverse impacts on birthing parents and their children. While obstetrics practices are increasingly encouraged to use existing evidence-based screening tools, there is little data describing the extent to which screening practices and subsequent referrals to care are implemented in clinical settings. The Screening and Treatment Enhancement for Perinatal Depression (STEPS for PPD) study aims to characterize PND screening and referral procedures and identify areas for system improvements. We describe a protocol for an observational study, guided by implementation science frameworks, examining the role of embedded perinatal social workers in managing PND across Mass General Brigham system obstetrics clinics. Our mixed-methods approach integrates qualitative and quantitative data from a variety of sources, including electronic health records, patient-reported surveys, and qualitative interviews, to capture complex screening and referral practices across a large academic medical system. We aim to characterize nuances within the screening and referral system and identify barriers and facilitators to care to inform future hybrid-implementation effectiveness research and improve patient outcomes.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Study participant flow across pregnancy and the postpartum.

References

    1. Dagher RK, Bruckheim HE, Colpe LJ, Edwards E, White DB. Perinatal depression: challenges and opportunities. J Womens Health (Larchmt). 2021;30(2):154–9. doi: 10.1089/jwh.2020.8862 - DOI - PMC - PubMed
    1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (5th Edition). APA, 2013.
    1. Ko JY, Rockhill KM, Tong VT, Morrow B, Farr SL. Trends in postpartum depressive symptoms—27 states, 2004, 2008, and 2012. Morbidity Mortality Weekly Rep. 2017;66(6):153. - PMC - PubMed
    1. Ko J, Farr S, Dietz P, Robbins C. Depression and treatment among U.S. pregnant and nonpregnant women of reproductive age, 2005-2009. J Womens Health (Larchmt). 2012;21(8):830–6. - PMC - PubMed
    1. Van Niel M, Payne J. Perinatal depression: a review. Cleveland Clinic J Med. 2020;87(5):273–7. - PubMed