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. 2025 Aug;170(2):751-759.
doi: 10.1002/ijgo.70082. Epub 2025 Mar 24.

Bacteriuria profile and antimicrobial sensitivity among pregnant women attending antenatal care at Jazan and Sabyia general hospitals, Jazan Region, KSA: A cross-sectional study

Isameldin Elamin Medani  1 , Ahlam Hakami  1 , Ahmed Altraifi  1 , Maha Murtada Abdelmageed  1 , Ali Khormi  1 , Uma Chourasia  1 , Essam Falagy  2 , Ahmad Alnamy  3 , Bishi Moukli  3 , Sarah Mnaa  3 , Maha Alanazi  4 , Manal Jamali  5 , Ali Maashi  6 , Hayat Khudhayr  6 , Sara Eltigani  6 , Nouf Shahhar  6 , Safia Muqri  6 , Nada Makein  7 , Yasser Majrabi  6
Affiliations

Bacteriuria profile and antimicrobial sensitivity among pregnant women attending antenatal care at Jazan and Sabyia general hospitals, Jazan Region, KSA: A cross-sectional study

Isameldin Elamin Medani et al. Int J Gynaecol Obstet. 2025 Aug.

Abstract

Background: Bacteria in urine, which is known as bacteriuria, is divided clinically into two types: symptomatic, where the patient experiences urinary complaints, and asymptomatic (ASB), in which the patient has no complaints. Pregnant women who have ASB may later develop symptomatic urinary tract infection, which is considered one of the most common bacterial infections in pregnancy and which, if untreated, can result in serious adverse pregnancy outcomes.

Objective: The goal of this research was to find out the prevalence of bacteriuria and its related factors among pregnant women in the Jazan Region, Saudi Arabia, recognize correlated microbial organisms, and identify the antimicrobial profile.

Methods: A cross-sectional study was conducted at Jazan and Sabyia general hospitals from June 28, 2023 to June 28, 2024. A systematic random sample of 392 pregnant women was selected. Urine samples were collected from them for bacteriological cultures and antimicrobial sensitivity testing. Data were collected and analyzed.

Results: Out of 392 participants, 19% had bacteriuria. Most women were aged 26-35, overweight, and resided in urban areas. The most common bacteria found were Escherichia coli (39.2%) and Klebsiella pneumoniae (17.6%). Antimicrobial sensitivity was highest for cefuroxime and vancomycin and lowest for erythromycin and penicillin. Significant predictors of bacteriuria were residence, body mass index, gestational age, hemoglobin levels, and hemoglobin A1c levels.

Conclusion: The study revealed a significant prevalence of bacteriuria among pregnant women in Jazan Region, highlighting the importance of routine screening and targeted interventions for high-risk groups. Effective antibiotic stewardship programs are essential to managing resistance patterns.

Keywords: UTI; antibiotic resistance; asymptomatic bacteriuria; microbial sensitivity.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Prevalence of bacteriuria among pregnant women attending Jazan General Hospital and Sabyia General Hospital, Jazan Region, Saudi Arabia, 2024 (n = 392).
FIGURE 2
FIGURE 2
Antibacterial sensitivity among pregnant women with bacteriuria (n = 74).
See this image and copyright information in PMC

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