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Comment
. 2025 Apr;122(13):e2503396122.
doi: 10.1073/pnas.2503396122. Epub 2025 Mar 24.

Bacteria on steroids

Natalia Mrnjavac  1 , William F Martin  1
Affiliations
Comment

Bacteria on steroids

Natalia Mrnjavac et al. Proc Natl Acad Sci U S A. 2025 Apr.
No abstract available

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Conflict of interest statement

Competing interests statement:The authors declare no competing interest.

Figures

Fig. 1.
Fig. 1.
Simplified summary of testosterone fermentation (1) in Phosphitispora sp. TUW77. Cob, cobalamine, or cobamide. Cobamides are a group of cobalt-containing compounds that include cobalamin and similar compounds that differ slightly with respect to the structure of the lower ligand (4). THF, tetrahydrofolate. “:,” cofactor electron pairs that bind methyl groups. The beige line symbolizes the plasma membrane. See Wang et al. (1) for details.
See this image and copyright information in PMC

Comment on

References

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    1. Modjewski L. D., et al. , Evidence for corrin biosynthesis in the last universal common ancestor. FEBS J. 292, 827–850 (2025). - PMC - PubMed
    1. Celeste L. R., et al. , Mechanism of N10-formyltetrahydrofolate synthetase derived from complexes with intermediates and inhibitors. Protein Sci. 21, 219–228 (2011). - PMC - PubMed

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