Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2025 Mar 8;20(5):2500-2508.
doi: 10.1016/j.radcr.2025.01.056. eCollection 2025 May.

Beyond the benign: A rare case report of myxoid pleomorphic liposarcoma

Arslan Ahmad  1 , Muhammad Ammar  1 , Muhammad Hasnain Saleem Choudary  1 , Muhammad Nouman Sadiq  1 , Rana Uzair Ahmad  1 , Nouman Aziz  1
Affiliations
Case Reports

Beyond the benign: A rare case report of myxoid pleomorphic liposarcoma

Arslan Ahmad et al. Radiol Case Rep. .

Abstract

Myxoid pleomorphic liposarcoma is a rare and aggressive subtype of soft tissue sarcomas (STS). It primarily arises from adipose tissue and exhibits a high rate of recurrence and metastatic potential. We report the case of a 35-year-old male gym trainer with a 5-month history of a painless, progressively enlarging mass on the right posterior aspect of chest, diagnosed with myxoid pleomorphic liposarcoma following imaging and histopathological evaluation of the excised specimen. Surgical excision with clear margins and adjuvant radiotherapy resulted in a favorable outcome with no recurrence at 7 months. This case emphasizes the importance of early diagnosis and multidisciplinary approach in managing a rare soft tissue sarcoma to prevent complications from a delayed intervention.

Keywords: Case report; Myxoid pleomorphic liposarcoma; Oncology; Soft tissue sarcoma.

PubMed Disclaimer

Figures

Fig 1:
Fig. 1
Preoperative picture showing a swelling location on the right side of back of chest, with lateralization on over-head abduction of the right arm.
Fig 2:
Fig. 2
CT films show a right sided mass lesion (arrowhead) in the intermuscular plane deep to latissimus dorsi muscle located lateral to, and extending inferiorly from the scapula. Underlying bone is unremarkable.
Fig 3:
Fig. 3
histological images of the Tru-Cut biopsy showing spindle cells with ovoid nuclei with tapering eosinophilic cytoplasm.
Fig 4:
Fig. 4
MRI Rt. Shoulder shows a well-defined lobulated heterogenous looking altered signal intensity lesion on T2WI/STIR; first row (axial), second row: left (coronal), right (sagittal).
Fig 5:
Fig. 5
MRI Rt. Shoulder shows mass lesion signals isointense to muscles on T1W1/FSE (first row, axial; second row, coronal), with postcontrast enhancement (third row: left, axial; right, coronal). Further, signal void of vessels is unremarkable.
Fig 6:
Fig. 6
Intraoperative picture showing excised lesion.
See this image and copyright information in PMC

References

    1. Siegel R.L., Miller K.D., Fuchs H.E., Jemal A. Cancer statistics, 2021. CA Cancer J Clin. 2021;71(1) - PubMed
    1. Sbaraglia M., Bellan E., Dei Tos A.P. The 2020 WHO classification of soft tissue tumours: news and perspectives. Pathologica. 2021;113(2):70. - PMC - PubMed
    1. Grünewald T.G., Alonso M., Avnet S., Banito A., Burdach S., Cidre-Aranaz F., et al. Sarcoma treatment in the era of molecular medicine. EMBO Mol Med. 2020;12(11) - PMC - PubMed
    1. Potter J.W., Jones K.B., Barrott J.J. Sarcoma–the standard-bearer in cancer discovery. Critic Rev Oncol/Hematol. 2018;126:1–5. - PMC - PubMed
    1. Levy A.D., Manning M.A., WB Al-Refaie, Miettinen M.M. Soft-tissue sarcomas of the abdomen and pelvis: radiologic-pathologic features, part 1—Common sarcomas. Radiographics. 2017;37(2) - PMC - PubMed

Publication types

LinkOut - more resources