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Review
. 2025 Mar 10:16:1536663.
doi: 10.3389/fphar.2025.1536663. eCollection 2025.

Effects of perioperative anesthetics on the postoperative prognosis of patients undergoing surgery for cervical cancer

Linyan Deng #  1   2   3 , Tingting Wang #  1   2   3 , Qiaofeng Zhang  1   2   3 , Shaofang Shu  1   2   3 , Xiangdong Chen  1   2   3
Affiliations
Review

Effects of perioperative anesthetics on the postoperative prognosis of patients undergoing surgery for cervical cancer

Linyan Deng et al. Front Pharmacol. .

Abstract

Cervical cancer is a common malignancy among women, and tumor excision is the most common surgical intervention. Anesthetics used during surgery include general intravenous, volatile, local anesthetics, sedative and analgesic. Studies have shown that the selection of perioperative surgical methods and anesthetics may influence postoperative metastasis and cancer recurrence through their effects on the immune response and tumor cells. Therefore, the selection of perioperative anesthetic has a significant impact on patients undergoing surgery for cervical cancer. This study summarizes the effects and related mechanisms of common anesthetics on the prognosis of patients undergoing surgery for cervical cancer to provide a basis for developing more optimal anesthesia protocols.

Keywords: anesthetics; cervical cancer; metastasis; perioperative; recurrence.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Different effects of sevoflurane on cervical cancer cells.
FIGURE 2
FIGURE 2
Effects of anesthetics on cervical cancer cells. Shorter duration of sevoflurane and isoflurane use may have a tumor promoting effect on cervical cancer.
See this image and copyright information in PMC

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