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. 2025 Aug;46(8):4071-4072.
doi: 10.1007/s10072-025-08137-3. Epub 2025 Mar 25.

AChR-blocking antibodies and complement system dynamics: evaluating their interplay and clinical implications in myasthenia gravis

Florencia Aguirre  1 , Mariano E Justo  2   3 , Lucía Cialdella  1 , Mariela L Paz  4   5
Affiliations

AChR-blocking antibodies and complement system dynamics: evaluating their interplay and clinical implications in myasthenia gravis

Florencia Aguirre et al. Neurol Sci. 2025 Aug.
No abstract available

Keywords: AChR-binding antibodies; AChR-blocking antibodies; Complement system; Myasthenia gravis.

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Conflict of interest statement

Declarations. Ethical approval: None. Conflict of interest: None.

References

    1. Seok HY, Eun MY (2025) Acetylcholine receptor blocking antibodies in myasthenia gravis: reevaluating their role in disease severity and mechanisms. Neurol Sci. https://doi.org/10.1007/s10072-025-08070-5 . Online ahead of print - DOI - PubMed
    1. Aguirre F, Justo ME, Cialdella L, Paz ML (2024) AChR-blocking antibodies and complement system dynamics: evaluating their interplay and clinical implications in myasthenia Gravis. Neurol Sci 46:1827–1832. https://doi.org/10.1007/s10072-024-07889-8 - DOI - PubMed
    1. Besinger UA, Toyka KV, Hömberg M et al (1983) Myasthenia gravis: long-term correlation of binding and bungarotoxin blocking antibodies against acetylcholine receptors with changes in disease severity. Neurology 33:1316–1316. https://doi.org/10.1212/WNL.33.10.1316 - DOI - PubMed
    1. Howard FM, Lennon VA, Finley J et al (1987) Clinical correlations of antibodies that bind, block, or modulate human acetylcholine receptors in myasthenia gravis a. Ann N Y Acad Sci 505:526–538. https://doi.org/10.1111/j.1749-6632.1987.tb51321.x - DOI - PubMed
    1. Kang SY, Oh JH, Song SK et al (2015) Both binding and blocking antibodies correlate with disease severity in myasthenia gravis. Neurol Sci 36:1167–1171. https://doi.org/10.1007/s10072-015-2236-8 - DOI - PubMed

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