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Case Reports
. 2025 Apr;31(4):791-794.
doi: 10.3201/eid3104.241812.

Bartonella quintana Endocarditis and Pauci-Immune Glomerulonephritis in Patient with Known Risk Factors, USA, 2024

Weibo Yu, Christopher N Tymchuk, Ran Zhuo, Daniel P Stefanko, Cody Forsyth, Colette J Matysiak Match, Sukantha Chandrasekaran, Gregory A Fishbein, Shangxin Yang
Case Reports

Bartonella quintana Endocarditis and Pauci-Immune Glomerulonephritis in Patient with Known Risk Factors, USA, 2024

Weibo Yu et al. Emerg Infect Dis. 2025 Apr.

Abstract

We report an unexpected case of Bartonella quintana endocarditis and pauci-immune glomerulonephritis in a patient without known risk factors in Los Angeles, California, USA, highlighting that infection can occur in the general population without a history of homelessness. The diagnosis was challenging and made definitively through extensive diagnostic tests and multidisciplinary investigation.

Keywords: Bartonella quintana; California; United States; bacteria; endocarditis; glomerulonephritis.

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Figures

Figure 1
Figure 1
Intraoperative image showing verrucous excrescences on the mitral valve from a patient with Bartonella quintana endocarditis and pauci-immune glomerulonephritis, California, USA.
Figure 2
Figure 2
Histopathology images from a patient with Bartonella quintana endocarditis and pauci-immune glomerulonephritis, California, USA. A) Hematoxylin and eosin stain revealing infiltration of neutrophils and lymphocytes as well as precipitation of fibrin. B) Gram stain showing numerous degenerated bacteria clumped together, mimicking gram-positive cocci. C) Warthin-Starry stain showing numerous rod-shaped bacteria.
See this image and copyright information in PMC

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