Author Correction: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells

Viktor Glaser^{1

2}, Christian Flugel^{1

2}, Jonas Kath^{1

2}, Weijie Du^{1

2}, Vanessa Drosdek^{1

2}, Clemens Franke^{1

2}, Maik Stein^{1

2}, Axel Pruß³, Michael Schmueck-Henneresse^{1

2}, Hans-Dieter Volk^{1

2

4

5}, Petra Reinke^{1

2}, Dimitrios L Wagner^{6

7

8

9}

Affiliations

¹ Berlin Center for Advanced Therapies (Becat), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.
² BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.
³ Institute of Transfusion Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Campus Charité Mitte, Charitéplatz 1, Berlin, 10117, Germany.
⁴ Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.
⁵ CheckImmune GmbH, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.
⁶ Berlin Center for Advanced Therapies (Becat), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany. dimitrios-l.wagner@charite.de.
⁷ BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany. dimitrios-l.wagner@charite.de.
⁸ Institute of Transfusion Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Campus Charité Mitte, Charitéplatz 1, Berlin, 10117, Germany. dimitrios-l.wagner@charite.de.
⁹ Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany. dimitrios-l.wagner@charite.de.

PMID: 40140907
PMCID: PMC11938680
DOI: 10.1186/s13059-025-03548-z

Published Erratum

Author Correction: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells

Viktor Glaser et al. Genome Biol. 2025.

. 2025 Mar 26;26(1):71.

doi: 10.1186/s13059-025-03548-z.

Authors

Affiliations

¹ Berlin Center for Advanced Therapies (Becat), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.
² BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.
³ Institute of Transfusion Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Campus Charité Mitte, Charitéplatz 1, Berlin, 10117, Germany.
⁴ Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.
⁵ CheckImmune GmbH, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany.
⁶ Berlin Center for Advanced Therapies (Becat), Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany. dimitrios-l.wagner@charite.de.
⁷ BIH Center for Regenerative Therapies (BCRT), Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany. dimitrios-l.wagner@charite.de.
⁸ Institute of Transfusion Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Campus Charité Mitte, Charitéplatz 1, Berlin, 10117, Germany. dimitrios-l.wagner@charite.de.
⁹ Institute of Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität Zu Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, 13353, Germany. dimitrios-l.wagner@charite.de.

PMID: 40140907
PMCID: PMC11938680
DOI: 10.1186/s13059-025-03548-z

No abstract available

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Erratum for

Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells.
Glaser V, Flugel C, Kath J, Du W, Drosdek V, Franke C, Stein M, Pruß A, Schmueck-Henneresse M, Volk HD, Reinke P, Wagner DL. Glaser V, et al. Genome Biol. 2023 Apr 24;24(1):89. doi: 10.1186/s13059-023-02928-7. Genome Biol. 2023. PMID: 37095570 Free PMC article.

References

1. Glaser V, Flugel C, Kath J, et al. Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells. Genome Biol. 2023;24:89. 10.1186/s13059-023-02928-7. - PMC - PubMed
1. Gaudelli NM, Lam DK, Rees H, et al. Directed evolution of adenine base editors with increased activity and therapeutic application. Nat Biotechnol. 2020;38:7. 10.1038/s41587-020-0491-6. - PubMed

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Author Correction: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells

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Author Correction: Combining different CRISPR nucleases for simultaneous knock-in and base editing prevents translocations in multiplex-edited CAR T cells

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