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Case Reports
. 2024 May 21:5:100112.
doi: 10.1016/j.jhlto.2024.100112. eCollection 2024 Aug.

Do not forget about the left ventricle after lung transplantation for pulmonary hypertension

Affiliations
Case Reports

Do not forget about the left ventricle after lung transplantation for pulmonary hypertension

Christine Adib et al. JHLT Open. .

Abstract

Patients with severe pulmonary arterial hypertension undergoing lung transplant are at risk of developing left ventricular dysfunction (LVD). We present a case of severe LVD following transplant to highlight the challenges in diagnosis and suggest measures to reduce the risk of cardiogenic shock and end-organ injury.

Keywords: cardiogenic shock; left ventricular dysfunction; lung transplantation; primary graft dysfunction; pulmonary arterial hypertension.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Acknowledgments: None. This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Figures

Figure 1
Figure 1
Pretransplant transthoracic echocardiography. Apical 4-chamber view in diastole revealing severe right ventricular enlargement with compression of the left ventricle and a small pericardial effusion.

References

    1. Huston J.H., Brittain E.L., Robbins I.M. Pulmonary hypertension and right ventricular failure: lung transplant versus heart-lung transplant. Cardiol Clin. 2020;38:269–281. doi: 10.1016/j.ccl.2020.01.002. - DOI - PubMed
    1. Manders E., Bogaard H.J., Handoko M.L., et al. Contractile dysfunction of left ventricular cardiomyocytes in patients with pulmonary arterial hypertension. J Am Coll Cardiol. 2014;64:28–37. doi: 10.1016/j.jacc.2014.04.031. - DOI - PubMed
    1. Verbelen T., Van Cromphaut S., Rega F., Meyns B. Acute left ventricular failure after bilateral lung transplantation for idiopathic pulmonary arterial hypertension. J Thorac Cardiovasc Surg. 2013;145:e7–e9. doi: 10.1016/j.jtcvs.2012.10.020. - DOI - PubMed
    1. Gupta S., Torres F., Bollineni S., Mohanka M., Kaza V. Left ventricular dysfunction after lung transplantation for pulmonary arterial hypertension. Transplant Proc. 2015;47:2732–2736. doi: 10.1016/j.transproceed.2015.07.040. - DOI - PubMed
    1. Bîrsan T., Kranz A., Mares P., et al. Transient left ventricular failure following bilateral lung transplantation for pulmonary hypertension. J Heart Lung Transplant. 1999;18:304–309. doi: 10.1016/s1053-2498(98)00050-3. - DOI - PubMed

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