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Comment

. 2025 Mar 28;387(6741):1353-1354.

doi: 10.1126/science.adw3646. Epub 2025 Mar 27.

Beyond hedonic eating

Dana M Small^{1

2

3}

Affiliations

Affiliations

¹ Departments of Neurology and Neurosurgery, Medicine, and Psychology, McGill University, Montreal, QC, Canada.
² Research Institute of the McGill University Health Center (RI-MUHC), Montreal, QC, Canada.
³ Modern Diet and Physiology Research Centre, Montreal Neurological Institute- Hospital, Montreal, QC, Canada.

PMID: 40146849
DOI: 10.1126/science.adw3646

Comment

Beyond hedonic eating

Dana M Small. Science. 2025.

. 2025 Mar 28;387(6741):1353-1354.

doi: 10.1126/science.adw3646. Epub 2025 Mar 27.

Author

Dana M Small^{1

2

3}

Affiliations

¹ Departments of Neurology and Neurosurgery, Medicine, and Psychology, McGill University, Montreal, QC, Canada.
² Research Institute of the McGill University Health Center (RI-MUHC), Montreal, QC, Canada.
³ Modern Diet and Physiology Research Centre, Montreal Neurological Institute- Hospital, Montreal, QC, Canada.

PMID: 40146849
DOI: 10.1126/science.adw3646

Abstract

A dopaminergic brain circuit drives food consumption in mice.

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Comment on

Hedonic eating is controlled by dopamine neurons that oppose GLP-1R satiety.
Zhu Z, Gong R, Rodriguez V, Quach KT, Chen X, Sternson SM. Zhu Z, et al. Science. 2025 Mar 28;387(6741):eadt0773. doi: 10.1126/science.adt0773. Epub 2025 Mar 28. Science. 2025. PMID: 40146831 Free PMC article.

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