Physical Activity, Nutritional Behaviours and Depressive Symptoms in Women with Hashimoto's Disease

Abstract

An important element of supporting pharmacotherapy in hypothyroidism is a pro-health lifestyle, with rational nutrition and recreational physical activity playing important roles. Objectives: The aim of this study was to analyse selected behavioural determinants of depressive states in women with Hashimoto's disease. Methods: This study was conducted among 219 women aged 20-50 using the following: (i) the author's questionnaire of nutritional behaviours for people with hypothyroidism (QNB); (ii) the International Physical Activity Questionnaire (IPAQ); and (iii) the Beck Depression Scale (SDB). Statistical analysis was performed in Statistica 13.1 and JASP programmes, using Spearman's R correlation analysis, the Kruskal-Wallis analysis of variance and regression analysis at a significance level of α = 0.05. Results: It was found that depressive symptoms were weakly negatively associated with moderate physical activity. At the same time, women with low levels of depressive symptoms demonstrated higher levels of vigorous physical activity than women with moderate and high levels of depression. Depression symptoms decreased with the implementation of some dietary recommendations, including the consumption of products rich in iodine, iron, zinc, selenium, vitamin D, vitamin A and polyunsaturated omega-3 fatty acids. The occurrence of constipation, requiring a high-fibre diet, was positively associated with symptoms of depression. Regression analysis showed that the model consisting of all QNB items explained 18% of depression symptoms. Conclusions: In summary, among women with Hashimoto's disease, moderate physical activity and some rational dietary choices were associated with a lower intensity of depressive symptoms. Promoting a healthy lifestyle may help improve the mental state of patients with Hashimoto's disease.

Keywords: depression; diet; hypothyroidism; lifestyle.