Association between the metabolic syndrome and the irritable bowel syndrome: a cross-sectional study among a sample of Lebanese adults

Abstract

Evidence of an association between metabolic syndrome (MetS) and irritable bowel syndrome (IBS) is emerging but is still inconclusive. The current cross-sectional study was conducted to explore the relationship between the two syndromes in a sample of Lebanese adults (n 221; mean age: 43·36 years; 62·9 % females), recruited from a large urban university and its neighbouring community. MetS was diagnosed based on the International Diabetes Federation criteria, and IBS was assessed using the Birmingham IBS scale. Logistic regression analyses were performed taking MetS and its components as dependent variables and IBS and its subscales as independent variables. Covariates included socio-demographic, dietary and lifestyle variables. MetS was positively associated with visual analogue scale (VAS) IBS (total scale (Beta = 4·59, P = 0·029) and VAS-diarrhoea subscale (Beta = 4·96, P = 0·008). Elevated blood pressure (Beta = 5·02, P = 0·007), elevated fasting blood sugar (Beta = 4·19, P = 0·033) and elevated waist circumference (Beta = 5·38, P = 0·010) were positively associated with VAS-Diarrhoea subscale. MetS and IBS were found to be positively associated in a sample of the Lebanese adult population. We suggest that it might be of value to screen for either condition if one of the syndromes exists. Future longitudinal studies are essential to establish a causal relationship between the two syndromes to further understand the commonality related to pathogenesis and explore potential underlying mechanisms.

Keywords: Adults; Irritable Bowel Syndrome; Lebanon; Metabolic Syndrome.