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. 1985 May;47(5):735-8.
doi: 10.1016/S0006-3495(85)83972-2.

The rate of diffusion of Ca2+ and Ba2+ in a nerve cell body

E Nasi, D Tillotson

The rate of diffusion of Ca2+ and Ba2+ in a nerve cell body

E Nasi et al. Biophys J. 1985 May.

Abstract

A spectrophotometric method was developed to directly measure the diffusion rate of Ca2+ and some other ions in nerve cell bodies, using pulsed ionophoretic injections and an optical microprobe to record locally absorbance changes of the dye arsenazo III. We report here that Ca2+ and Ba2+ diffuse at approximately the same rate in nerve soma cytoplasm, having effective diffusion coefficients in the range of 7-12 X 10(-7) cm2/s, while identical measurements conducted in an electrolytic solution yielded values of 5.2 X 10(-6) cm2/s for Ca and 5.4 X 10(-6) cm2/s for Ba. The results are discussed in relation to the mechanisms that regulate the intracellular concentration of free Ca.

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References

    1. J Physiol. 1967 Sep;192(2):407-36 - PubMed
    1. J Physiol. 1969 Feb;200(2):497-527 - PubMed
    1. Proc Natl Acad Sci U S A. 1975 Jan;72(1):187-90 - PubMed
    1. J Gen Physiol. 1976 Apr;67(4):433-67 - PubMed
    1. J Gen Physiol. 1977 Sep;70(3):355-84 - PubMed

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