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Review
. 2025 Apr 1;92(4):221-231.
doi: 10.3949/ccjm.92a.24098.

Most elderly patients with subclinical hypothyroidism do not need to be treated

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Free article
Review

Most elderly patients with subclinical hypothyroidism do not need to be treated

Risheng Xu et al. Cleve Clin J Med. .
Free article

Abstract

Whether subclinical hypothyroidism should be treated in elderly patients (≥ 65 years) is controversial. The authors argue for a personalized, wait-and-see approach rather than universal treatment, pointing out that randomized clinical trials have not shown that levothyroxine treatment makes any difference in terms of hard clinical end points, quality of life, or hypothyroid symptom relief in elderly patients with this condition.

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