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Editorial
. 2025 Mar 18:16:1588902.
doi: 10.3389/fpsyt.2025.1588902. eCollection 2025.

Editorial: Treatment resistant depression (TRD): epidemiology, clinic, burden and treatment

Andrea Fiorillo  1 , Koen Demyttenaere  2 , Vassilis Martiadis  3 , Giovanni Martinotti  4
Affiliations
Editorial

Editorial: Treatment resistant depression (TRD): epidemiology, clinic, burden and treatment

Andrea Fiorillo et al. Front Psychiatry. .
No abstract available

Keywords: TRD (treatment-resistant depression); burden; depression; epidemiology; pharmacological treatment.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Comment on

  • Editorial on the Research Topic Treatment resistant depression (TRD): epidemiology, clinic, burden and treatment

References

    1. McIntyre RS, Alsuwaidan M, Baune BT, Berk M, Demyttenaere K, Goldberg JF, et al. . Treatment-resistant depression: definition, prevalence, detection, management, and investigational interventions. World Psychiatry. (2023) 22:394–412. - PMC - PubMed
    1. Sampogna G, Toni C, Catapano P, Della Rocca B, Di Vincenzo M, Luciano M, et al. . New trends in personalized treatment of depression. Curr Opin Psychiatry. (2024) 37:3–8. doi: 10.1097/YCO.0000000000000903 - DOI - PubMed
    1. Luciano M, Sampogna G, Della Rocca B, Simonetti A, De Fazio P, Di Nicola M, et al. . The impact of affective temperaments on suicidal ideation and behaviors: results from an observational multicentric study on patients with mood disorders. Brain Sci. (2023) 13:117. doi: 10.3390/brainsci13010117 - DOI - PMC - PubMed
    1. Demyttenaere K. What is treatment resistance in psychiatry? A “difficult to treat” concept. World Psychiatry. (2019) 18:354–5. doi: 10.1002/wps.20677 - DOI - PMC - PubMed
    1. Food and Drug Administration . (2019). Available online at: https://www.fda.gov/news-events/press-announcements/fda-approves-new-nas... (Accessed February 21, 2025).

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