Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Jan;16(1):73-6.

Pathogenesis of corneal damage from pseudomonas exotoxin A

B H Iglewski, R P Burns, I K Gipson
  • PMID: 401777

Pathogenesis of corneal damage from pseudomonas exotoxin A

B H Iglewski et al. Invest Ophthalmol Vis Sci. 1977 Jan.

Abstract

Pseudomonas aeruginosa exotoxin A was injected into rabbit corneas. Death of epithelial, endothelial, and stromal cells resulted, and necrosis of the cornea followed. Control eyes with exotoxin neutralized by specific antitoxin showed minimal damage. A dose-response pattern was evident. Antitoxin neutralization of pseudomonas exotoxin A in corneal ulcers may have possible therapeutic implications.

PubMed Disclaimer

Publication types

Substances

LinkOut - more resources