Corticosteroids in Fulminant Myocarditis Associated With Viral Infection

Florent Huang^{1

2}, Enrico Ammirati³, Maharajah Ponnaiah⁴, Santiago Montero⁵, Nadia Aïssaoui⁶, Albert Ariza Solé⁷, Martin Balik⁸, Eduardo Barge-Caballero⁹, Jeroen J H Bunge¹⁰, Hergen Buscher¹¹, Clément Delmas¹², Dirk W Donker^{13

14}, Christoph Fisser¹⁵, Guillaume Franchineau¹⁶, Justin Fried¹⁷, Francisco José Hernández-Pérez¹⁸, Joshua Ihle¹⁹, Jae-Seung Jung²⁰, Teresa Lόpez-Sobrino²¹, Jamie McCanny²², Armand Mekontso Dessap²³, Henrique Muglia²⁴, Shinichiro Ohshimo²⁵, Sunghoon Park²⁶, Romain Persichini^{27

28}, Beatriz Porral²⁹, Roberto Roncon-Albuquerque Jr³⁰, Alessandro Sionis³¹, Pauline Yeung Ng³², Alain Combes^{2

33}, Matthieu Schmidt^{2

33}; FULLMOON Study Group

Affiliations

¹ ACTION Study Group, Sorbonne Université, Assistance Publique-Hôpitaux de Paris, La Pitié-Salpêtrière Hospital, Departement of Cardiology, France (F.H.).
² Sorbonne Université, Assistance Publique-Hôpitaux de Paris, La Pitié-Salpêtrière Hospital, Medical Intensive Care Unit, France (F.H., A.C., M.S.).
³ De Gasperis Cardio Center and Transplant Center, Niguarda Hospital, Milan, Italy (E.A.).
⁴ Fondation pour l'Innovation en Cardiométabolisme et Nutrition (ICAN) Intelligence and Omics, Institute of Cardiometabolism and Nutrition, La Pitié-Salpêtrière Hospital, Paris, France (M.P.).
⁵ Acute Cardiovascular Care Unit, Cardiology, Hospital Germans Trias i Pujol, Departament de Medicina, Universitat Autònoma de Barcelona, Spain (S.M.).
⁶ Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Cochin Hospital, Intensive Care Unit, Paris, France (N.A.).
⁷ Intensive Cardiac Care Unit, Cardiology Department, Bellvitge University Hospital, Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigació Biomèdica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain (A.A.S.).
⁸ Department of Anaesthesiology and Intensive Care, General University Hospital, Prague, Czech Republic (M.B.).
⁹ Cardiology Department, Complejo Hospitalario Universitario de A Coruña (CHUAC), Instituto de Investigación Biomédica de A Coruña (INIBIC), CIBERCV, Spain (E.B.-C.).
¹⁰ Department of Intensive Care Adults and Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands (J.J.H.B.).
¹¹ Intensive Care Unit, St Vincent Hospital, Sydney, NSW, Australia (H.B.).
¹² Department of Cardiology, Rangueil University Hospital, Toulouse, France (C.D.).
¹³ Intensive Care Center, University Medical Center Utrecht, the Netherlands (D.W.D.).
¹⁴ Cardiovascular and Respiratory Physiology, TechMed Center, University of Twente, Enschede, the Netherlands (D.W.D.).
¹⁵ Intensive Care Unit, University Medical Centre Regensburg, Germany (C.F.).
¹⁶ Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Bichat-Claude Bernard Hospital, Department of Intensive Care Medicine and Infectious Diseases, France (G.F.).
¹⁷ Department of Cardiology, Columbia University Irving Medical Center/New York-Presbyterian Hospital, NY (J.F.).
¹⁸ Advanced Heart Failure and Transplant Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro, Madrid, Spain (F.J.H.-P.).
¹⁹ Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (J.I.).
²⁰ Department of Thoracic and Cardiovascular Surgery, Korea University Anam Hospital, Seoul, South Korea (J.-S.J.).
²¹ Department of Cardiology, Hospital Clínic Barcelona, Spain (T.L.-S.).
²² Intensive Care Unit, Guy's and St Thomas' NHS Foundation Trust Hospital, London, United Kingdom (J.M.C.).
²³ Assistance Publique-Hôpitaux de Paris, Mondor Hospital, Medical Intensive Care Unit, Créteil, France (A.M.D.).
²⁴ Intensive Care Unit, Erasme Hospital, Brussels, Belgium (H.M.).
²⁵ Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan (S.O.).
²⁶ Intensive Care Unit, Hallym University Sacred Heart Hospital, Anyang, South Korea (S.P.).
²⁷ Medical-Surgical Intensive Care Unit, Félix Guyon Hospital, CHU de La Réunion, France (R.P.).
²⁸ Service de réanimation et Soins-Continus-CH de Saintes, France (R.P.).
²⁹ Intensive Care Department, Hospital Alvaro Cunqueiro, Vigo, Spain (B.P.).
³⁰ Intensive Care Unit, Saint João Hospital, Porto, Portugal (R.R.-A.J.).
³¹ Intensive Cardiac Care Unit, Department of Cardiology, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Universitat Autònoma de Barcelona, Spain (A.S.).
³² Critical Care Medicine Unit, Queen Mary Hospital, Hong Kong, China (P.Y.N.).
³³ Sorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS_1166-iCAN, Institute of Cardiometabolism and Nutrition, Paris, France (A.C., M.S.).

PMID: 40177751
DOI: 10.1161/CIRCHEARTFAILURE.124.012399

Corticosteroids in Fulminant Myocarditis Associated With Viral Infection

Florent Huang et al. Circ Heart Fail. 2025 May.

. 2025 May;18(5):e012399.

doi: 10.1161/CIRCHEARTFAILURE.124.012399. Epub 2025 Apr 3.

Authors

Affiliations

¹ ACTION Study Group, Sorbonne Université, Assistance Publique-Hôpitaux de Paris, La Pitié-Salpêtrière Hospital, Departement of Cardiology, France (F.H.).
² Sorbonne Université, Assistance Publique-Hôpitaux de Paris, La Pitié-Salpêtrière Hospital, Medical Intensive Care Unit, France (F.H., A.C., M.S.).
³ De Gasperis Cardio Center and Transplant Center, Niguarda Hospital, Milan, Italy (E.A.).
⁴ Fondation pour l'Innovation en Cardiométabolisme et Nutrition (ICAN) Intelligence and Omics, Institute of Cardiometabolism and Nutrition, La Pitié-Salpêtrière Hospital, Paris, France (M.P.).
⁵ Acute Cardiovascular Care Unit, Cardiology, Hospital Germans Trias i Pujol, Departament de Medicina, Universitat Autònoma de Barcelona, Spain (S.M.).
⁶ Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Cochin Hospital, Intensive Care Unit, Paris, France (N.A.).
⁷ Intensive Cardiac Care Unit, Cardiology Department, Bellvitge University Hospital, Bioheart, Grup de Malalties Cardiovasculars, Institut d'Investigació Biomèdica de Bellvitge, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain (A.A.S.).
⁸ Department of Anaesthesiology and Intensive Care, General University Hospital, Prague, Czech Republic (M.B.).
⁹ Cardiology Department, Complejo Hospitalario Universitario de A Coruña (CHUAC), Instituto de Investigación Biomédica de A Coruña (INIBIC), CIBERCV, Spain (E.B.-C.).
¹⁰ Department of Intensive Care Adults and Department of Cardiology, Erasmus Medical Center, Rotterdam, the Netherlands (J.J.H.B.).
¹¹ Intensive Care Unit, St Vincent Hospital, Sydney, NSW, Australia (H.B.).
¹² Department of Cardiology, Rangueil University Hospital, Toulouse, France (C.D.).
¹³ Intensive Care Center, University Medical Center Utrecht, the Netherlands (D.W.D.).
¹⁴ Cardiovascular and Respiratory Physiology, TechMed Center, University of Twente, Enschede, the Netherlands (D.W.D.).
¹⁵ Intensive Care Unit, University Medical Centre Regensburg, Germany (C.F.).
¹⁶ Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Bichat-Claude Bernard Hospital, Department of Intensive Care Medicine and Infectious Diseases, France (G.F.).
¹⁷ Department of Cardiology, Columbia University Irving Medical Center/New York-Presbyterian Hospital, NY (J.F.).
¹⁸ Advanced Heart Failure and Transplant Unit, Department of Cardiology, Hospital Universitario Puerta de Hierro, Madrid, Spain (F.J.H.-P.).
¹⁹ Intensive Care Unit, Alfred Hospital, Melbourne, VIC, Australia (J.I.).
²⁰ Department of Thoracic and Cardiovascular Surgery, Korea University Anam Hospital, Seoul, South Korea (J.-S.J.).
²¹ Department of Cardiology, Hospital Clínic Barcelona, Spain (T.L.-S.).
²² Intensive Care Unit, Guy's and St Thomas' NHS Foundation Trust Hospital, London, United Kingdom (J.M.C.).
²³ Assistance Publique-Hôpitaux de Paris, Mondor Hospital, Medical Intensive Care Unit, Créteil, France (A.M.D.).
²⁴ Intensive Care Unit, Erasme Hospital, Brussels, Belgium (H.M.).
²⁵ Department of Emergency and Critical Care Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Japan (S.O.).
²⁶ Intensive Care Unit, Hallym University Sacred Heart Hospital, Anyang, South Korea (S.P.).
²⁷ Medical-Surgical Intensive Care Unit, Félix Guyon Hospital, CHU de La Réunion, France (R.P.).
²⁸ Service de réanimation et Soins-Continus-CH de Saintes, France (R.P.).
²⁹ Intensive Care Department, Hospital Alvaro Cunqueiro, Vigo, Spain (B.P.).
³⁰ Intensive Care Unit, Saint João Hospital, Porto, Portugal (R.R.-A.J.).
³¹ Intensive Cardiac Care Unit, Department of Cardiology, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Universitat Autònoma de Barcelona, Spain (A.S.).
³² Critical Care Medicine Unit, Queen Mary Hospital, Hong Kong, China (P.Y.N.).
³³ Sorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM) UMRS_1166-iCAN, Institute of Cardiometabolism and Nutrition, Paris, France (A.C., M.S.).

PMID: 40177751
DOI: 10.1161/CIRCHEARTFAILURE.124.012399

No abstract available

Keywords: biopsy; hospitals; lactates; viral load; virus diseases.

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Conflict of interest statement

Dr Huang reports personal fees and congress registration fees from AstraZeneca outside the submitted work. Dr Schmidt reports lecture fees from Getinge, Drager, and Xenios outside the submitted work. Dr Combes reports grants from Getinge and personal fees from Getinge, Baxter, and Xenios outside the submitted work. Dr Ammirati received an Italian Ministry Grant (GR-2019-12368506). The other authors report no conflicts.

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Corticosteroids in Fulminant Myocarditis Associated With Viral Infection

Affiliations

Corticosteroids in Fulminant Myocarditis Associated With Viral Infection

Authors

Affiliations

Conflict of interest statement

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LinkOut - more resources

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Medical