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Review
. 2025 May;109(3):705-720.
doi: 10.1016/j.mcna.2024.12.011. Epub 2025 Feb 21.

Severe Pneumonia

Patrick R Ching  1 , Laura L Pedersen  2
Affiliations
Review

Severe Pneumonia

Patrick R Ching et al. Med Clin North Am. 2025 May.

Abstract

Severe pneumonia is a leading cause of mortality and morbidity worldwide. Being a complex condition caused by a variety of microorganisms including bacteria, viruses, and fungi, it requires intensive care. A combination of early initiation of antimicrobial therapy and adjunctive nonantimicrobial interventions improve patient outcomes. This article reviews the most recent data on the epidemiology, microbiology, diagnosis, and management of severe pneumonia.

Keywords: COVID-19; Community-acquired infections; Critical illness; Hospitalization; Intensive care unit; Pneumonia; Steroids; Therapeutics.

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Conflict of interest statement

Disclosures The authors have nothing to disclose.

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