Letter to the editor: author response for "why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review"

Ignacio J Ansotegui¹, Jean Bousquet^{2

3

4

5}, Giorgio Walter Canonica⁶, Pascal Demoly^{7

8}, Rene Maximiliano Gómez^{9

10}, Eli O Meltzer¹¹, Margarita Murrieta-Aguttes¹², Robert M Naclerio¹³, Nelson Rosario Filho¹⁴, Glenis K Scadding^{15

16}

Affiliations

¹ Department of Allergy & Immunology, Hospital Quirónsalud Bizkaia, Bilbao, Spain.
² Institute of Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
³ Freie Universität Berlin, Berlin, Germany.
⁴ Humboldt-Universität zu Berlin, Berlin, Germany.
⁵ Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Humboldt-Universität zu Berlin, Berlin, Germany.
⁶ Personalized Medicine Asthma & Allergy Clinic, Humanitas University & Research Hospital, Milano, Italy.
⁷ Department of Pulmonology, Division of Allergy, University Hospital of Montpellier, Montpellier, France.
⁸ IDESP, University of Montpellier - INSERM, Montpellier, France.
⁹ Faculty of Health Sciences, Catholic University of Salta, Salta, Argentina.
¹⁰ Ayre Foundation/Alas Medical Institute, Salta, Argentina.
¹¹ Department of Pediatrics, Division of Allergy and Immunology, University of California San Diego, La Jolla, CA, USA.
¹² Sanofi, Neuilly-sur- Seine, France.
¹³ Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, USA.
¹⁴ Department of Pediatrics, Federal University of Paraná, Paraná, Brazil.
¹⁵ RNENT Hospital, London, UK.
¹⁶ Department of Immunity & Infection, University College London, London, UK.

Ignacio J Ansotegui et al. Curr Med Res Opin. 2025 Mar.

. 2025 Mar;41(3):457-459.

doi: 10.1080/03007995.2025.2488951. Epub 2025 Apr 12.

¹ Department of Allergy & Immunology, Hospital Quirónsalud Bizkaia, Bilbao, Spain.
² Institute of Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
³ Freie Universität Berlin, Berlin, Germany.
⁴ Humboldt-Universität zu Berlin, Berlin, Germany.
⁵ Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Humboldt-Universität zu Berlin, Berlin, Germany.
⁶ Personalized Medicine Asthma & Allergy Clinic, Humanitas University & Research Hospital, Milano, Italy.
⁷ Department of Pulmonology, Division of Allergy, University Hospital of Montpellier, Montpellier, France.
⁸ IDESP, University of Montpellier - INSERM, Montpellier, France.
⁹ Faculty of Health Sciences, Catholic University of Salta, Salta, Argentina.
¹⁰ Ayre Foundation/Alas Medical Institute, Salta, Argentina.
¹¹ Department of Pediatrics, Division of Allergy and Immunology, University of California San Diego, La Jolla, CA, USA.
¹² Sanofi, Neuilly-sur- Seine, France.
¹³ Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, MD, USA.
¹⁴ Department of Pediatrics, Federal University of Paraná, Paraná, Brazil.
¹⁵ RNENT Hospital, London, UK.
¹⁶ Department of Immunity & Infection, University College London, London, UK.