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. 2025 Feb 28;21(1):313-319.
doi: 10.5114/aoms/202123. eCollection 2025.

The role of GSDMs in the immune microenvironment of prostate cancer and their impact on patient prognosis: a comprehensive analysis based on the TCGA-PRAD database

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The role of GSDMs in the immune microenvironment of prostate cancer and their impact on patient prognosis: a comprehensive analysis based on the TCGA-PRAD database

Kai Liu et al. Arch Med Sci. .
No abstract available

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
A – The relationship between GSDMs and immune cell infiltration; B – Correlation between GSDMs and matrix immune score; C – GSDMs relationship with survival curve, correlation between risk factors of D.C.OX prognostic model and GSDMs, D – Risk factor scores were correlated with major immune cells

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References

    1. Slaufova M, Karakaya T, Di Filippo M, Hennig P, Beer HD. The gasdermins: a pore-forming protein family expressed in the epidermis. Front Immunol 2023; 14: 1254150. - PMC - PubMed
    1. Du T, Gao J, Li P, et al. . Pyroptosis, metabolism, and tumor immune microenvironment. Clin Transl Med 2021; 11: e492. - PMC - PubMed
    1. DePeaux K, Delgoffe GM. Metabolic barriers to cancer immunotherapy. Nat Rev Immunol 2021; 21: 785–97. - PMC - PubMed
    1. Jiang J, Xu Y, Chen D, et al. . Pan-cancer analysis of immune checkpoint receptors and ligands in various cells in the tumor immune microenvironment. Aging 2024; 16: 11683–728. - PMC - PubMed
    1. Bao X, Sun M, Meng L, Zhang H, Yi X, Zhang P. Applications of pyroptosis activators in tumor immunotherapy. Mater Today Bio 2024; 28: 101191. - PMC - PubMed

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