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. 2025 Mar;55(1):1-10.
doi: 10.5624/isd.20240139. Epub 2025 Jan 15.

Diagnostic accuracy of artificial intelligence in the detection of maxillary sinus pathology using computed tomography: A concise systematic review

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Diagnostic accuracy of artificial intelligence in the detection of maxillary sinus pathology using computed tomography: A concise systematic review

Asmaa T Uthman et al. Imaging Sci Dent. 2025 Mar.

Abstract

Purpose: This study was performed to assess the performance and accuracy of artificial intelligence (AI) in the detection and diagnosis of maxillary sinus pathologies using computed tomography (CT)/cone-beam computed tomography (CBCT) imaging.

Materials and methods: A comprehensive literature search was conducted across 4 databases: Google Scholar, BioMed Central (BMC), ProQuest, and PubMed. Combinations of keywords such as "DCNN," "deep learning," "convolutional neural network," "machine learning," "predictive modeling," and "data mining" were used to identify relevant articles. The study included articles that were published within the last 5 years, written in English, available in full text, and focused on diagnostic accuracy.

Results: Of an initial 530 records, 12 studies with a total of 3,349 patients (7,358 images) were included. All articles employed deep learning methods. The most commonly tested pathologies were maxillary rhinosinusitis and maxillary sinusitis, while the most frequently used AI models were convolutional neural network architectures, including ResNet and DenseNet, YOLO, and U-Net. DenseNet and ResNet architectures have demonstrated superior precision in detecting maxillary sinus pathologies due to their capacity to handle deeper networks without overfitting. The performance in detecting maxillary sinus pathology varied, with an accuracy ranging from 85% to 97%, a sensitivity of 87% to 100%, a specificity of 87.2% to 99.7%, and an area under the curve of 0.80 to 0.91.

Conclusion: AI with various architectures has been used to detect maxillary sinus abnormalities on CT/CBCT images, achieving near-perfect results. However, further improvements are needed to increase accuracy and consistency.

Keywords: Artificial Intelligence; Computed Tomography, X-Ray; Maxillary Sinus; Pathology.

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Figures

Fig. 1
Fig. 1. PRISMA flowchart for systematic review. PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-Analyses, BMC: BioMed Central, AI: artificial intelligence, MS: maxillary sinus.

References

    1. Xu J, Zeng B, Egger J, Wang C, Smedby Ö, Jiang X, et al. A review on AI-based medical image computing in head and neck surgery. Phys Med Biol. 2022;67:17TR01 - PubMed
    1. Majumder SK, Gupta A, Gupta S, Ghosh N, Gupta PK. Multi-class classification algorithm for optical diagnosis of oral cancer. J Photochem Photobiol B. 2006;85:109–117. - PubMed
    1. Obuchowicz R, Strzelecki M, Piórkowski A. Clinical applications of artificial intelligence in medical imaging and image processing - a review. Cancers (Basel) 2024;16:1870. - PMC - PubMed
    1. Hsiao YJ, Yang J, Resnik RR, Suzuki JB. Prevalence of maxillary sinus pathology based on cone-beam computed tomography evaluation of multiethnicity dental school population. Implant Dent. 2019;28:356–366. - PubMed
    1. Yalcin E, Ozturk EM. Association between accessory maxillary ostium, Haller cell, and sinus pathologies in cone-beam computed tomography. J Stomatol. 2022;75:187–194.