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. 2025 Apr 2;6(1):59-62.
doi: 10.1515/rir-2025-0007. eCollection 2025 Mar.

Insights into the clinical and immunological significance of anti-α-fodrin antibodies in systemic lupus erythematosus

Fernanda Espinosa-Bautista  1 , Varna Ramos-Rosillo  1 , Yadira Vazquez-Panchos  1 , Fernanda Bocanegra-Zamora  1 , Valentin Jimenez-Rojas  1 , Ricardo Márquez-Velasco  1 , Luis M Amezcua-Guerra  1   2
Affiliations

Insights into the clinical and immunological significance of anti-α-fodrin antibodies in systemic lupus erythematosus

Fernanda Espinosa-Bautista et al. Rheumatol Immunol Res. .
No abstract available

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Conflict of interest statement

Conflict of interest The authors declare no competing interest.

Figures

Figure 1
Figure 1
Anti-α-fodrin antibodies in systemic lupus erythematosus (SLE). Panel A presents the levels of anti-α-fodrin IgA and IgG antibodies in SLE patients, with a dotted line marking the positivity threshold. Panel B shows the absence of a significant correlation between anti-α-fodrin IgA levels and disease activity. Panel C illustrates a significant inverse correlation between anti-α-fodrin IgA levels and serum CCL11/eotaxin levels, while panel D depicts a similar correlation with CCL2/MCP-1 levels. In contrast, panels E–G demonstrate no significant associations between anti-α-fodrin IgG levels and disease activity, CCL11/eotaxin, or CCL2/MCP-1 levels, respectively.
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