HIV-exposed uninfected umbilical cord blood haematopoietic stem/progenitor cells differ immunophenotypically from those from HIV unexposed umbilical cord blood but have similar expansion and colony-forming properties in vitro
- PMID: 40195551
- DOI: 10.1038/s41409-025-02574-6
HIV-exposed uninfected umbilical cord blood haematopoietic stem/progenitor cells differ immunophenotypically from those from HIV unexposed umbilical cord blood but have similar expansion and colony-forming properties in vitro
Conflict of interest statement
Competing interests: MSP has received research grants from the South African Medical Research Council, the Bill and Melinda Gates Foundation, the South African National Health Laboratory Service Research Trust, The National Research Foundation (South Africa) and the Wellcome Trust. MSP is a co-founder and non-remunerated board member of Antion Biosciences and Altera Biosciences and is also CSO of the latter. CLH is a non-remunerated board member of DKMS Africa, a not-for-profit organisation. Ethics approval: Ethics approval for this work was obtained from the University of Pretoria Faculty of Health Sciences Research Ethics Committee, approval number 102/2020. All enrolled mothers gave written informed consent, for collection of umbilical cord blood after delivery of the infant, for the purposes of the study. All methods were performed in accordance with the relevant guidelines and regulations.
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