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. 2025 Aug 1;57(8):1769-1779.
doi: 10.1249/MSS.0000000000003702. Epub 2025 Mar 10.

Muscular Strength in Cancer Patients: Proposed Normative Values

Buck W Covington 2nd  1 , Luke Krynski, Lea Haverbeck Simon, Michael Lazio, Brooke Mattocks, Jesse Hayward, Reid Hayward
Affiliations

Muscular Strength in Cancer Patients: Proposed Normative Values

Buck W Covington 2nd et al. Med Sci Sports Exerc. .

Abstract

Purpose: The aim of this study is to propose muscular strength normative data tables for the cancer population and observe the effects of exercise training on categorical placement.

Methods: Data from cancer survivors ( n = 659) encompassing various cancer types across all cancer stages were used for this study. Participants completed assessments to estimate one-repetition maximum (1RM) for both chest press and leg press, in addition to a test of maximum effort dominant handgrip strength. Strength-to-weight ratio (SWR) and handgrip strength values were divided into categories by sex and age and compared with normative values from the apparently healthy population as reported by the American College of Sports Medicine.

Results: Comparison of mean SWR and handgrip strength values for the cancer population to the apparently healthy normative data resulted in each age/sex group being classified as "average" or lower. Of the 30 age/sex classification groups for the cancer population, 23 demonstrated mean strength values in the lowest category of their respective assessment.

Conclusions: Normative data derived from the apparently healthy population may not be an appropriate comparison for the cancer population and may not be sensitive enough to detect categorical improvements in muscular strength resulting from exercise training. We provide an initial data set that could serve as a first step in the development of normative strength data for this population.

Keywords: EXERCISE TRAINING; HANDGRIP STRENGTH; NORMATIVE DATA; ONCOLOGY; STRENGTH-TO-WEIGHT RATIO.

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