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Book

Glomeruloid Hemangioma

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Glomeruloid Hemangioma

Jay Nguyen et al.
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Excerpt

Glomeruloid hemangiomas are rare benign vascular lesions. These tumors were first described by Chan et al in the 1990s. Glomeruloid hemangiomas are strongly associated with systemic diseases, most commonly polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome and less commonly multicentric Castleman disease (MCD). Glomeruloid hemangiomas may also exist in the absence of an associated systemic disease. POEMS syndrome, also known as Crow-Fukase syndrome, Takatsuki syndrome, and polyneuropathy-endocrinopathy-plasma cell dyscrasia syndrome, was first described by Crow in 1956.

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Conflict of interest statement

Disclosure: Jay Nguyen declares no relevant financial relationships with ineligible companies.

Disclosure: Elizabeth Hughes declares no relevant financial relationships with ineligible companies.

References

    1. Gupta V, Rai A, Mridha AR, Sharma VK. Multiple glomeruloid hemangiomas without POEMS syndrome. Indian J Dermatol Venereol Leprol. 2016 Jul-Aug;82(4):442-4. - PubMed
    1. Roy RR, Shimada K, Hasegawa H. A Case of Oral Glomeruloid Hemangioma Without Systemic Conditions. Cureus. 2022 Jan;14(1):e21705. - PMC - PubMed
    1. Jacobson-Dunlop E, Liu H, Simpson EL, White CR, White KP. Glomeruloid hemangiomas in the absence of POEMS syndrome. J Cutan Pathol. 2012 Apr;39(4):402-3. - PubMed
    1. Perdaens C, De Raeve H, Goossens A, Sennesael J. POEMS syndrome characterized by glomeruloid angioma, osteosclerosis and multicentric Castleman disease. J Eur Acad Dermatol Venereol. 2006 Apr;20(4):480-1. - PubMed
    1. Scheers C, Kolivras A, Corbisier A, Gheeraert P, Renoirte C, Theunis A, de Saint-Aubain N, André J, Sass U, Song M. POEMS syndrome revealed by multiple glomeruloid angiomas. Dermatology. 2002;204(4):311-4. - PubMed

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