Synthesis and crystal structure of 5-{(E)-[(1 H-indol-3-ylformamido)-imino]-meth-yl}-2-meth-oxy-phenyl propane-1-sulfonate

Abstract

In the title mol-ecule, C₂₀H₂₁N₃O₅S, the methyl-ideneformohydrazide and meth-oxy-benzene groups are almost coplanar, with the indolyl group being rotated farther from the plane. The mol-ecules in the crystal structure form chains parallel to the a-axis direction through N-H⋯O hydrogen-bonding inter-actions. Neighbouring chains are linked by N-H⋯O contacts to form a three-dimensional network.

Keywords: crystal structure; indole; sulfonate.

Figure 1

Synthesis of the novel title compound (3), which incorporates two bioactive moieties, indole and sulfonate, linked through a hydrazine linker.

Figure 2

The mol­ecular structure of the title compound showing 50% probability displacement ellipsoids.

Figure 3

(a) A segment of the crystal structure showing mol­ecules linked through N—H⋯O hydrogen bonds (green dotted lines). (b) The crystal structure viewed down the b axis with C—H⋯O inter­actions shown as black dotted lines.