NCCN Guidelines® Insights: Testicular Cancer, Version 2.2025

Timothy Gilligan¹, Daniel W Lin², Nabil Adra³, Aditya Bagrodia⁴, Darren R Feldman⁵, Kosj Yamoah⁶, Rahul Aggarwal⁷, Thenappan Chandrasekar⁸, Daniel Costa⁹, Alexandra Drakaki¹⁰, Scott Eggener¹¹, Hamid Emamekhoo¹², Daniel M Geynisman¹³, Laura Graham¹⁴, Peter Humphrey¹⁵, Harshraj Leuva¹⁶, Ellis G Levine¹⁷, Amy Luckenbaugh¹⁸, Benjamin L Maughan¹⁹, Bradley McGregor²⁰, Paul Monk²¹, Joel Picus²², Phillip Pierorazio²³, Soroush Rais-Bahrami²⁴, Zachery Reichert²⁵, Jean-Claude Rwigema²⁶, Philip Saylor²⁷, Ankeet Shah²⁸, Sumit Shah²⁹, Nirmish Singla³⁰, Kanishka Sircar³¹, David VanderWeele³², Ali Zhumkhawala³³, Sarah Montgomery³⁴, Bailee Sliker³⁴

Affiliations

¹ Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
² Fred Hutchinson Cancer Center.
³ Indiana University Melvin and Bren Simon Comprehensive Cancer Center.
⁴ UC San Diego Moores Cancer Center.
⁵ Memorial Sloan Kettering Cancer Center.
⁶ Moffitt Cancer Center.
⁷ UCSF Helen Diller Family Comprehensive Cancer Center.
⁸ UC Davis Comprehensive Cancer Center.
⁹ UT Southwestern Simmons Comprehensive Cancer Center.
¹⁰ UCLA Jonsson Comprehensive Cancer Center.
¹¹ The UChicago Medicine Comprehensive Cancer Center.
¹² University of Wisconsin Carbone Cancer Center.
¹³ Fox Chase Cancer Center.
¹⁴ University of Colorado Cancer Center.
¹⁵ Yale Cancer Center/Smilow Cancer Hospital.
¹⁶ Fred & Pamela Buffett Cancer Center.
¹⁷ Roswell Park Comprehensive Cancer Center.
¹⁸ Vanderbilt-Ingram Cancer Center.
¹⁹ Huntsman Cancer Institute at the University of Utah.
²⁰ Dana-Farber/Brigham and Women's Cancer Center.
²¹ The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
²² Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
²³ Abramson Cancer Center at the University of Pennsylvania.
²⁴ O'Neal Comprehensive Cancer Center at UAB.
²⁵ University of Michigan Rogel Cancer Center.
²⁶ Mayo Clinic Comprehensive Cancer Center.
²⁷ Mass General Cancer Center.
²⁸ Duke Cancer Institute.
²⁹ Stanford Cancer Institute.
³⁰ Johns Hopkins Kimmel Cancer Center.
³¹ The University of Texas MD Anderson Cancer Center.
³² Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
³³ City of Hope National Medical Center.
³⁴ National Comprehensive Cancer Network.

PMID: 40203876
DOI: 10.6004/jnccn.2025.0018

Practice Guideline

NCCN Guidelines® Insights: Testicular Cancer, Version 2.2025

Timothy Gilligan et al. J Natl Compr Canc Netw. 2025 Apr.

. 2025 Apr;23(4):e250018.

doi: 10.6004/jnccn.2025.0018.

Authors

Affiliations

¹ Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute.
² Fred Hutchinson Cancer Center.
³ Indiana University Melvin and Bren Simon Comprehensive Cancer Center.
⁴ UC San Diego Moores Cancer Center.
⁵ Memorial Sloan Kettering Cancer Center.
⁶ Moffitt Cancer Center.
⁷ UCSF Helen Diller Family Comprehensive Cancer Center.
⁸ UC Davis Comprehensive Cancer Center.
⁹ UT Southwestern Simmons Comprehensive Cancer Center.
¹⁰ UCLA Jonsson Comprehensive Cancer Center.
¹¹ The UChicago Medicine Comprehensive Cancer Center.
¹² University of Wisconsin Carbone Cancer Center.
¹³ Fox Chase Cancer Center.
¹⁴ University of Colorado Cancer Center.
¹⁵ Yale Cancer Center/Smilow Cancer Hospital.
¹⁶ Fred & Pamela Buffett Cancer Center.
¹⁷ Roswell Park Comprehensive Cancer Center.
¹⁸ Vanderbilt-Ingram Cancer Center.
¹⁹ Huntsman Cancer Institute at the University of Utah.
²⁰ Dana-Farber/Brigham and Women's Cancer Center.
²¹ The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute.
²² Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine.
²³ Abramson Cancer Center at the University of Pennsylvania.
²⁴ O'Neal Comprehensive Cancer Center at UAB.
²⁵ University of Michigan Rogel Cancer Center.
²⁶ Mayo Clinic Comprehensive Cancer Center.
²⁷ Mass General Cancer Center.
²⁸ Duke Cancer Institute.
²⁹ Stanford Cancer Institute.
³⁰ Johns Hopkins Kimmel Cancer Center.
³¹ The University of Texas MD Anderson Cancer Center.
³² Robert H. Lurie Comprehensive Cancer Center of Northwestern University.
³³ City of Hope National Medical Center.
³⁴ National Comprehensive Cancer Network.

PMID: 40203876
DOI: 10.6004/jnccn.2025.0018

Abstract

The NCCN Guidelines for Testicular Cancer provide recommendations for the multidisciplinary approach to the diagnostic workup, treatment, and follow-up for testicular germ cell tumors, including both seminoma and nonseminoma. These NCCN Guidelines Insights discuss the current treatment recommendations and supporting clinical data for seminomas as presented in Version 2.2025 of the NCCN Guidelines for Testicular Cancer.

PubMed Disclaimer

References

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Supplementary concepts

Actions

LinkOut - more resources

Full Text Sources
- Sheridan PubFactory
Medical
- MedlinePlus Health Information

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

NCCN Guidelines® Insights: Testicular Cancer, Version 2.2025

Affiliations

NCCN Guidelines® Insights: Testicular Cancer, Version 2.2025

Authors

Affiliations

Abstract

References

Publication types

MeSH terms

Supplementary concepts

LinkOut - more resources

Full Text Sources

Medical