Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Apr 10;57(1):46-49.
doi: 10.5114/ait.2025.147585. Epub 2025 Feb 17.

Cerebral vasculitis secondary to pneumococcal meningitis. Plasmapheresis as adjuvant therapy. Case report

Almudena Domínguez  1 , Carmen Rosa Fraga  1 , Roger Ayala  1 , Pedro Conde  1 , Daida García  1 , Alberto Cereijo  1
Affiliations

Cerebral vasculitis secondary to pneumococcal meningitis. Plasmapheresis as adjuvant therapy. Case report

Almudena Domínguez et al. Anaesthesiol Intensive Ther. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

none.

Figures

FIGURE 1
FIGURE 1
Initial magnetic resonance imaging: multiple confluent focal areas of restricted diffusion bilaterally and symmetrically, predominantly in the frontal and bilateral periatrial regions, and in the semioval centres, consistent with cytotoxic damage, suggesting acute ischaemic lesions in the context of probable associated vasculitis. Bilateral frontal punctate susceptibility artefacts, within the signal alteration, suggestive of small haemorrhagic foci
FIGURE 2
FIGURE 2
Magnetic resonance imaging on 16th day of hospitalisation
FIGURE 3
FIGURE 3
Magnetic resonance imaging after 2 months of hospitalisation
See this image and copyright information in PMC

References

    1. Chen X, Bai Y, Cui W, Wang Z, Zhang G, Xu Y, et al. . Effects of B7-H3 on the inflammatory response and expression of MMP-9 in mice with pneumococcal meningitis. J Mol Neurosci 2013; 50: 146-153. 10.1007/s12031-012-9885-3. - DOI - PubMed
    1. Vergouwen MD, Schut ES, Troost D, van de Beek D. Diffuse cerebral intravascular coagulation and cerebral infarction in pneumococcal meningitis. Neurocrit Care 2010; 13: 217-227. 10.1007/s12028-010-9387-5. - DOI - PubMed
    1. Khedher A, Sma N, Slama D, Fraj N, Hachfi W, Boussarsar M. Cerebral. vasculitis complicating pneumococcal meningitis. Eur J Case Rep Intern Med 2018; 5: 000819. 10.12890/2018_000819. - DOI - PMC - PubMed
    1. Engelen-Lee JY, Brouwer MC, Aronica E, van de Beek D. Pneumococcal meningitis: clinical-pathological correlations (MeninGene-Path). Acta Neuropathol Commun 2016; 4: 26. 10.1186/s40478-016-0297-4. - DOI - PMC - PubMed
    1. Koedel U, Frankenberg T, Kirschnek S, Ober-maier B, Häcker H, Paul R, Häcker G. Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis. PLoS Pathog 2009; 5: e1000461. 10.1371/journal.ppat.1000461. - DOI - PMC - PubMed

LinkOut - more resources