Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2025 Jun 1;37(6):710-716.
doi: 10.1097/MEG.0000000000002969. Epub 2025 Mar 18.

A comparison between the Bowel Ultrasound Score and International Bowel Ultrasound Segmental Activity Score based on ileocolonoscopy in patients with Crohn's disease

Ilhami Yuksel  1   2 , Yavuz Cagir  1 , Muhammed Bahaddin Durak  3 , Ali Atay  1 , Mucahit Ergul  1 , Oguz Ozturk  1 , Emir Tugrul Keskin  1 , Ahmet Burak Fedai  1 , Muhammed Mustafa Ince  1 , Erdogan Deniz  1 , Zeki Mesut Yalin Kilic  1
Affiliations
Comparative Study

A comparison between the Bowel Ultrasound Score and International Bowel Ultrasound Segmental Activity Score based on ileocolonoscopy in patients with Crohn's disease

Ilhami Yuksel et al. Eur J Gastroenterol Hepatol. .

Abstract

Background and aim: We aimed to compare two main existing scores, the Bowel Ultrasound Score (BUSS) and the International Bowel Ultrasound Segmental Activity Score (IBUS-SAS) to predict simplified endoscopic activity score for Crohn's disease (SES-CD).

Methods: A cross-sectional study was conducted to evaluate the disease activity in Crohn's disease (CD) patients with ileal involvement between November 2019 and February 2024. Endoscopic remission for CD was accepted as SES-CD ≤2.

Results: A total of 56 adult patients with CD (male: 38, 68%, median age: 40.5 years) were included in the study, the median duration of the disease was 8.4 years. The cutoff value for BUSS to determine endoscopic remission was 3.9, whereas the cutoff value for IBUS-SAS to establish endoscopic remission was 24.4. BUSS and SES-CD had a strong positive correlation ( P < 0.001), BUSS and IBUS-SAS had a high positive correlation ( P < 0.001), and BUSS and C-reactive protein had a slightly positive correlation ( P < 0.001).

Conclusion: This study revealed that the cutoff values for BUSS and IBUS-SAS in CD patients with endoscopic remission were 3.9 and 24.4, respectively. Furthermore, it was demonstrated that BUSS and IBUS-SAS highly correlate with endoscopic activity in the real-world cohort.

Keywords: Bowel Ultrasound Score; Crohn’s disease; International Bowel Ultrasound Segmental Activity Score; intestinal ultrasound.

PubMed Disclaimer

References

    1. Panés J, Bouzas R, Chaparro M, Gisbert JP, Martínez de Guereñu B, et al. Systematic review: the use of ultrasonography, computed tomography and magnetic resonance imaging for the diagnosis, assessment of activity and abdominal complications of Crohn’s disease. Aliment Pharmacol Ther. 2011; 34:125–45.
    1. Allocca M, Furfaro F, Fiorino G, Peyrin-Biroulet L, Danese S. Point-of-care ultrasound in inflammatory bowel disease. J Crohns Colitis. 2021; 15:143–151.
    1. Rimola J, Torres J, Kumar S, Taylor SA, Kucharzik T. Recent advances in clinical practice: advances in cross-sectional imaging in inflammatory bowel disease. Gut. 2022; 71:2587–2597.
    1. Goodsall TM, Nguyen TM, Parker CE, Ma C, Andrews JM, Jairath V, Bryant RV. Systematic review: gastrointestinal ultrasound scoring indices for inflammatory bowel disease. J Crohns Colitis. 2021; 15:125–142.
    1. Barchi A, D’Amico F, Zilli A, Furfaro F, Parigi TL, Fiorino G, et al. Recent advances in the use of ultrasound in Crohn’s disease. Expert Rev Med Devices. 2023; 20:1119–1129.

Publication types