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. 1985 Jun;30(6):443-50.

Müllerian dysgenesis

R E Varner, J B Younger, R E Blackwell
  • PMID: 4020785

Müllerian dysgenesis

R E Varner et al. J Reprod Med. 1985 Jun.

Abstract

The multifaceted syndrome of müllerian dysgenesis appears to represent a defect in mesodermal organization and is often associated with renal and skeletal anomalies. This report discusses the embryology, multifactorial etiology, clinical presentation and management of the syndrome from a historical standpoint and details our experience with 35 affected patients. Both Frank dilatation and McIndoe vaginoplasty appear to be acceptable means of therapy. The therapeutic success depends to a large extent on the psychosocial adaptation of the patient.

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