Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Jun 5;26(2):120-124.
doi: 10.23804/ejpd.2025.2190. Epub 2025 Apr 1.

Dental pain in children: pharmacological management

Affiliations
Free article
Review

Dental pain in children: pharmacological management

A Mohn et al. Eur J Paediatr Dent. .
Free article

Abstract

Background: The prevalence of dental pain is relatively high across the global population, primarily attributable to dental caries. School-age children and adolescents with caries, particularly those with caregivers from lower socioeconomic backgrounds, are more likely to experience dental pain. In very young children, pain modulation is not yet fully developed; thus, inadequate pain management may cause pain memory formation which can lead to altered pain responses later in life.

Materials: This review aims to provide an overview of the management of dental pain in children with pulpitis. To achieve this goal, a search was conducted in PubMed using relevant keywords. The literature investigation focused on the pharmacological management of paediatric pulpitis, including the treatment of associated complications.

Conclusion: Dental pain represents a significant public health concern. Pain due to endodontic emergency is different in younger children and should to be assessed with the use of an appropriate scales and treated with NSAID and/or acetoaminophen. The combination of ibuprofen and acetaminophen at fixed doses appears to be a viable option for dental pain treatment, although further randomised controlled trials (RCTs) are needed for confirmation. Antibiotics should only be used in cases involving local and/or systemic infectious complications. Opioids are not recommended for managing dental pain. Antibiotic prophylaxis is necessary only in selected cases and should not overshadow primary prevention, which remains the only true option for reducing the development of dental complications. Antibiotic Stewardship Programs (ASPs) could play a significant role in reducing inappropriate antibiotic prescriptions.

PubMed Disclaimer

References

Substances

LinkOut - more resources