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. 1985 Sep;55(3):877-80.
doi: 10.1128/JVI.55.3.877-880.1985.

mRNA activity of a Sindbis virus defective-interfering RNA

G Migliaccio, P Castagnola, A Leone, A Cerasuolo, S Bonatti

mRNA activity of a Sindbis virus defective-interfering RNA

G Migliaccio et al. J Virol. 1985 Sep.

Abstract

We obtained Sindbis defective-interfering particles by nine and undiluted passages of standard virus on chicken embryo fibroblasts. These particles contain a deleted 20S RNA molecule which has mRNA activity, as shown by translation in cell-free systems in vitro. In infected cells, this mRNA activity appeared to be totally inhibited except at very late times postinfection.

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