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Review
. 2025 May;36(2):371-387.
doi: 10.1016/j.pmr.2024.11.009. Epub 2024 Dec 9.

Considerations for Long COVID Rehabilitation in Women

Affiliations
Review

Considerations for Long COVID Rehabilitation in Women

Monica Verduzco-Gutierrez et al. Phys Med Rehabil Clin N Am. 2025 May.

Abstract

The coronavirus disease 2019 (COVID-19) pandemic has given rise to long COVID, a prolonged manifestation of severe acute respiratory syndrome coronavirus 2 infection, which presents with varied symptoms and conditions lasting beyond expected acute illness. Despite efforts, diagnostic and treatment approaches remain insufficient, particularly for women who experience higher prevalence rates. Rehabilitation professionals have played a crucial role during the pandemic. Individualized rehabilitation plans, encompassing various therapies and interdisciplinary collaborations, are essential. Addressing disparities and biological sex differences is paramount, requiring increased research, understanding, and advocacy for effective rehabilitative care tailored to all individuals affected by long COVID.

Keywords: Female; Gender differences; Long coronavirus disease; Myalgic encephalomyelitis; Post-acute sequelae of severe acute respiratory syndrome coronavirus 2; Postural orthostatic tachycardia syndrome; Women.

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Conflict of interest statement

Disclosures Dr M. Verduzco-Gutierrez is a Co-PI for AHRQ. Other authors have nothing to disclose.