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Published Erratum
. 2025 Apr 10;44(1):116.
doi: 10.1186/s13046-025-03373-z.

Correction: TSPAN18 facilitates bone metastasis of prostate cancer by protecting STIM1 from TRIM32-mediated ubiquitination

Qianghua Zhou #  1   2   3 , Xu Chen #  1   2 , Kai Yao #  3 , Yangjie Zhang #  1   2 , Haixia He  2   4 , Hao Huang  1   2 , Hao Chen  1   2 , Shengmeng Peng  1   2 , Ming Huang  1   2 , Liang Cheng  1   2 , Qiang Zhang  1   2 , Ruihui Xie  1   2 , Kaiwen Li  5   6 , Tianxin Lin  7   8   9 , Hai Huang  10   11   12
Affiliations
Published Erratum

Correction: TSPAN18 facilitates bone metastasis of prostate cancer by protecting STIM1 from TRIM32-mediated ubiquitination

Qianghua Zhou et al. J Exp Clin Cancer Res. .
No abstract available

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Figures

Fig. 6
Fig. 6
TSPAN18 promotes bone metastasis of PCa cells in vivo. a-b Representative images of bioluminescence (a) and X-ray (b) of bone metastasis through caudal artery injection. The red arrows show bone metastases. c Western blot analysis of TSPAN18 expression in stably TSPAN18-knockdown or TSPAN18-overexpressing cells and control cells. d TSPAN18-knockdown, TSPAN18-overexpressing and corresponding control PC-3 cells stably expressing luciferase were injected into nude mice through caudal artery, then the bone metastasis was weekly measured using an in vivo IVIS system. Representative bioluminescence images at indicated weeks from each group were shown. e Kaplan-Meier curves for metastasis-free survival of mice bearing PC-3 cells as indicated. f The counts of metastasis in indicated groups (n = 6/group). g Representative immunohistochemical images of micro-CT, H&E and luciferase, and immunofuorescent staining of E-cadherin (green) and N-cadherin (red) in each group as indicated. The nucleus is labeled with DAPI (blue). Scale bars: red, 50 μm. h The tumor volume to the bone volume ratio was calculated for each mouse and presented in the plot at right. *p < 0.05, **p < 0.01 student’s t test
Fig. 6
Fig. 6
TSPAN18 promotes bone metastasis of PCa cells in vivo. a-b Representative images of bioluminescence (a) and X-ray (b) of bone metastasis through caudal artery injection. The red arrows show bone metastases. c Western blot analysis of TSPAN18 expression in stably TSPAN18-knockdown or TSPAN18-overexpressing cells and control cells. d TSPAN18-knockdown, TSPAN18-overexpressing and corresponding control PC-3 cells stably expressing luciferase were injected into nude mice through caudal artery, then the bone metastasis was weekly measured using an in vivo IVIS system. Representative bioluminescence images at indicated weeks from each group were shown. e Kaplan-Meier curves for metastasis-free survival of mice bearing PC-3 cells as indicated. f The counts of metastasis in indicated groups (n = 6/group). g Representative immunohistochemical images of micro-CT, H&E and luciferase, and immunofuorescent staining of E-cadherin (green) and N-cadherin (red) in each group as indicated. The nucleus is labeled with DAPI (blue). Scale bars: red, 50 μm. h The tumor volume to the bone volume ratio was calculated for each mouse and presented in the plot at right. *p < 0.05, **p < 0.01 student’s t test
Supplemental Fig. 13
Supplemental Fig. 13
The representative bioluminescence images of the mice after 6 weeks of inoculations with indicated PC-3 cells
Supplemental Fig. 13
Supplemental Fig. 13
The representative bioluminescence images of the mice after 6 weeks of inoculations with indicated PC-3 cells
See this image and copyright information in PMC

Erratum for

References

    1. Zhou Q, Chen X, Yao K, Zhang Y, He H, Huang H, et al. TSPAN18 facilitates bone metastasis of prostate cancer by protecting STIM1 from TRIM32-mediated ubiquitination. J Exp Clin Cancer Res. 2023;42(1):195. - DOI - PMC - PubMed

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